UniProt:Q94IW5 CYP90D2

chain
  • chain:1-490
checksum 9EC2853BBAFBB88F
comment
  • FUNCTION Catalyzes the C6-oxidation step in brassinosteroids biosynthesis (PubMed:14615594). May convert 6-deoxoteasterone (6-deoxoTE) to 3-dehydro-6-deoxoteasterone (6-deoxo3DT, 6-deoxo3DHT), and teasterone (TE) to 3-dehydroteasterone (3DT, 3-DHT) (PubMed:14615594). Involved in the elongation of leaf sheaths and stems (PubMed:14615594).CATALYTIC ACTIVITY 6-deoxoteasterone + reduced [NADPH--hemoprotein reductase] + O2 = 3-dehydro-6-deoxoteasterone + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)COFACTOR Plant hormone biosynthesis; brassinosteroid biosynthesis.SUBCELLULAR LOCATION Expressed at low levels leaf blades, shoot apex and elongating stem.INDUCTION Down-regulated by brassinolide (BL) in ebisu dwarf (d2) mutant.DISRUPTION PHENOTYPE Plants show abnormalities in growth: inhibition of second internode elongation, shortened leaf sheaths, erect leaves, and deficiency in skotomorphogenesis. Treatment with exogenous brassinolide (BL) rescues the abnormal phenotype.SIMILARITY Belongs to the cytochrome P450 family.
created [InstanceEdit:2730779] Amarasinghe, V, 2012-12-04
databaseName UniProt
dbId 2730764
description
  • recommendedName: fullName evidence="4"Cytochrome P450 90D2 shortName evidence="4"OsCYP90D2 alternativeName: fullName evidence="4"3-dehydro-6-deoxoteasterone synthase ecNumber evidence="3"1.14.19.- alternativeName: fullName evidence="4"3-dehydroteasterone synthase ecNumber evidence="3"1.14.19.- alternativeName: fullName evidence="4"C6-oxidase
displayName UniProt:Q94IW5 CYP90D2
geneName
  • CYP90D2
  • D2
  • Os01g0197100
  • LOC_Os01g10040
  • P0419B01.11
identifier Q94IW5
isSequenceChanged false
keyword
  • Brassinosteroid biosynthesis
  • Heme
  • Iron
  • Lipid biosynthesis
  • Lipid metabolism
  • Membrane
  • Metal-binding
  • Monooxygenase
  • Oxidoreductase
  • Reference proteome
  • Steroid biosynthesis
  • Transmembrane
  • Transmembrane helix
modified [InstanceEdit:9939033] Weiser, Joel, 2025-02-21
name
  • CYP90D2
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • C90D2_ORYSJ
  • Q0JPW7
sequenceLength 490
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/Q94IW5