UniProt:Q7XM21 F3H-1

chain
  • chain:1-377
checksum E5704DAB62538B1E
comment
  • FUNCTION Catalyzes the 3-beta-hydroxylation of 2S-flavanones to 2R,3R-dihydroflavonols which are intermediates in the biosynthesis of flavonols, anthocyanidins, catechins and proanthocyanidins in plants. Converts (2S)-eriodictyol to (+)-taxifolin and (2S)-naringenin to (+)-(2R/3R)-dihydrokaempferol in vitro.CATALYTIC ACTIVITY a (2S)-flavan-4-one + 2-oxoglutarate + O2 = a (2R,3R)-dihydroflavonol + succinate + CO2COFACTOR Binds 1 Fe(2+) ion per subunit.COFACTOR Secondary metabolite biosynthesis; flavonoid biosynthesis.TISSUE SPECIFICITY Expressed at low levels in roots, leaves, stems and seeds.SIMILARITY Belongs to the iron/ascorbate-dependent oxidoreductase family.
created [InstanceEdit:2672435] D'Eustachio, P, 2012-11-27
databaseName UniProt
dbId 2672430
description
  • recommendedName: fullName evidence="6"Flavanone 3-dioxygenase 1 ecNumber evidence="4"1.14.11.9 alternativeName: fullName evidence="6"Flavanone 3-beta-hydroxylase 1 alternativeName: fullName evidence="5"Flavanone 3-hydroxylase 1 shortName evidence="5"OsF3H-1
displayName UniProt:Q7XM21 F3H-1
geneName
  • F3H-1
  • Os04g0662600
  • LOC_Os04g56700
  • OSJNBa0084K01.10
identifier Q7XM21
isSequenceChanged false
keyword
  • Dioxygenase
  • Flavonoid biosynthesis
  • Iron
  • Metal-binding
  • Oxidoreductase
  • Reference proteome
  • Vitamin C
modified [InstanceEdit:9939033] Weiser, Joel, 2025-02-21
name
  • F3H-1
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • FL3H1_ORYSJ
  • A0A0P0WFY8
  • C7J0Y2
sequenceLength 377
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/Q7XM21