UniProt:Q10E50 PLA2-III

chain
  • signal peptide:1-43
  • chain:44-163
checksum 2C33E13B60A28BD2
comment
  • FUNCTION PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. Releases lysophospholipids (LPLs) and free fatty acids (FFAs) from membrane phospholipids in response to hormones and other external stimuli.CATALYTIC ACTIVITY a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1-acyl-sn-glycero-3-phosphocholine + a fatty acid + H(+)COFACTOR Binds 1 Ca(2+) ion per subunit.ACTIVITY REGULATION Inhibited by EGTA.SUBCELLULAR LOCATION Belongs to the phospholipase A2 family.
created [InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference
databaseName UniProt
dbId 1162766
description
  • recommendedName: Phospholipase A2 homolog 3 ecNumber: 3.1.1.4
displayName UniProt:Q10E50 PLA2-III
geneName
  • PLA2-III
  • Os03g0708000
  • LOC_Os03g50030
  • OsJ_12288
  • OSJNBb0022E02.7
identifier Q10E50
isSequenceChanged false
keyword
  • Calcium
  • Direct protein sequencing
  • Disulfide bond
  • Hydrolase
  • Lipid degradation
  • Lipid metabolism
  • Metal-binding
  • Reference proteome
  • Secreted
  • Signal
modified [InstanceEdit:9852000] Weiser, Joel, 2023-11-03
name
  • PLA2-III
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • PLA23_ORYSJ
  • A0A0P0W1Z7
  • Q94GR5
sequenceLength 163
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/Q10E50