UniProt:P93844 PLD2

chain
  • chain:1-817
checksum 948AE6A40B32E12F
comment
  • FUNCTION Hydrolyzes glycerol-phospholipids at the terminal phosphodiesteric bond. Plays an important role in various cellular processes.CATALYTIC ACTIVITY a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1,2-diacyl-sn-glycero-3-phosphate + choline + H(+)COFACTOR C2 domain is a calcium-binding fold, and the binding promotes the protein association with membranes. A lower affinity toward calcium can be anticipated for PLD alpha due to the absence of two potential calcium ligands.SIMILARITY Belongs to the phospholipase D family. C2-PLD subfamily.
created [InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference
databaseName UniProt
dbId 1162746
description
  • recommendedName: Phospholipase D alpha 2 shortName: PLD alpha 2 ecNumber: 3.1.4.4 alternativeName: Choline phosphatase 2 alternativeName: Phosphatidylcholine-hydrolyzing phospholipase D 2
displayName UniProt:P93844 PLD2
geneName
  • PLD2
  • Os06g0604400
  • LOC_Os06g40190
  • OsJ_21907
  • P0481H08.5
identifier P93844
isSequenceChanged false
keyword
  • Calcium
  • Hydrolase
  • Lipid degradation
  • Lipid metabolism
  • Metal-binding
  • Reference proteome
  • Repeat
modified [InstanceEdit:9852000] Weiser, Joel, 2023-11-03
name
  • PLD2
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • PLDA2_ORYSJ
  • A0A0P0WYW9
  • Q0DB42
  • Q69X20
sequenceLength 817
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/P93844