UniProt:Q0DKY4 Os05g0135700

chain
  • chain:1-396
checksum 16FE43474045FEB9
comment
  • FUNCTION Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.CATALYTIC ACTIVITY L-methionine + ATP + H2O = S-adenosyl-L-methionine + phosphate + diphosphateCOFACTOR Binds 2 divalent ions per subunit. The metal ions interact primarily with the substrate (By similarity). Can utilize magnesium, manganese or cobalt (in vitro) (By similarity).COFACTOR Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate (By similarity).PATHWAY Amino-acid biosynthesis; S-adenosyl-L-methionine biosynthesis; S-adenosyl-L-methionine from L-methionine: step 1/1.SUBUNIT Homotetramer.SUBCELLULAR LOCATION Belongs to the AdoMet synthase family.
created [InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference
databaseName UniProt
dbId 1162670
description
  • recommendedName: S-adenosylmethionine synthase 1 shortName: AdoMet synthase 1 ecNumber evidence="5"2.5.1.6 alternativeName: Methionine adenosyltransferase 1 shortName: MAT 1
displayName UniProt:Q0DKY4 Os05g0135700
geneName
  • Os05g0135700
  • SAM1
  • SAMS
  • LOC_Os05g04510
  • OsJ_016271
  • P0519E07.14
identifier Q0DKY4
isSequenceChanged false
keyword
  • ATP-binding
  • Cobalt
  • Cytoplasm
  • Magnesium
  • Metal-binding
  • Nucleotide-binding
  • One-carbon metabolism
  • Potassium
  • Reference proteome
  • Transferase
modified [InstanceEdit:9939033] Weiser, Joel, 2025-02-21
name
  • SAM1
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • METK1_ORYSJ
  • P46611
  • Q6AVZ2
  • Q8VXC5
sequenceLength 396
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/Q0DKY4