UniProt:Q69RG7 4CLL7

chain
  • chain:1-558
checksum B2D55391D2FFC50D
comment
  • FUNCTION Carboxylate--CoA ligase that may use 4-coumarate as substrate. Follows a two-step reaction mechanism, wherein the carboxylate substrate first undergoes adenylation by ATP, followed by a thioesterification in the presence of CoA to yield the final CoA thioester.CATALYTIC ACTIVITY (E)-4-coumarate + ATP + CoA = (E)-4-coumaroyl-CoA + AMP + diphosphateCATALYTIC ACTIVITY (E)-4-coumarate + ATP + H(+) = (E)-4-coumaroyl-AMP + diphosphateCATALYTIC ACTIVITY (E)-4-coumaroyl-AMP + CoA = (E)-4-coumaroyl-CoA + AMP + H(+)COFACTOR Both substrate-binding domains (SBD1 and SBD2) are involved in the substrate recognition, and are sufficient to confer the substrate specificity.SIMILARITY Belongs to the ATP-dependent AMP-binding enzyme family.
created [InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference
databaseName UniProt
dbId 1162470
description
  • recommendedName: 4-coumarate--CoA ligase-like 7 ecNumber evidence="1"6.2.1.12
displayName UniProt:Q69RG7 4CLL7
geneName
  • 4CLL7
  • Os07g0280200
  • LOC_Os07g17970
  • P0474B11.33
identifier Q69RG7
isSequenceChanged false
keyword
  • ATP-binding
  • Ligase
  • Magnesium
  • Nucleotide-binding
  • Reference proteome
modified [InstanceEdit:9852000] Weiser, Joel, 2023-11-03
name
  • 4CLL7
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • 4CLL7_ORYSJ
  • B7F1I2
sequenceLength 558
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/Q69RG7