UniProt:Q0J8A4 GAPC1

chain
  • initiator methionine:
  • chain:2-337
checksum 3A8154CF7A06A603
comment
  • FUNCTION Key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Essential for the maintenance of cellular ATP levels and carbohydrate metabolism (By similarity).CATALYTIC ACTIVITY D-glyceraldehyde 3-phosphate + phosphate + NAD(+) = (2R)-3-phospho-glyceroyl phosphate + NADH + H(+)BIOPHYSICOCHEMICAL PROPERTIES Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 1/5.SUBUNIT Homotetramer.SUBCELLULAR LOCATION By gibberellin.PTM Phosphorylated after gibberellin treatment.MISCELLANEOUS Plants contain two types of GAPDH: cytosolic forms which participate in glycolysis and chloroplast forms which participate in photosynthesis. All the forms are encoded by distinct genes.SIMILARITY Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
created [InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference
databaseName UniProt
dbId 1162096
description
  • recommendedName: Glyceraldehyde-3-phosphate dehydrogenase 1, cytosolic ecNumber: 1.2.1.12 alternativeName: PP38
displayName UniProt:Q0J8A4 GAPC1
geneName
  • GAPC1
  • GAPC
  • GAPDH
  • GPC
  • Os08g0126300
  • LOC_Os08g03290
  • OJ1163_G08.15
  • OsJ_024858
identifier Q0J8A4
isSequenceChanged false
keyword
  • 3D-structure
  • Cytoplasm
  • Direct protein sequencing
  • Glycolysis
  • NAD
  • Oxidoreductase
  • Reference proteome
modified [InstanceEdit:9939033] Weiser, Joel, 2025-02-21
name
  • GAPC1
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • G3PC1_ORYSJ
  • B7EIW3
  • Q42977
  • Q6ZK60
sequenceLength 337
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/Q0J8A4