UniProt:Q10N21 APX1

chain
  • initiator methionine:
  • chain:2-250
checksum 637D70B191CC92E9
comment
  • FUNCTION Plays a key role in hydrogen peroxide removal.CATALYTIC ACTIVITY L-ascorbate + H2O2 = L-dehydroascorbate + 2 H2OCOFACTOR Binds 1 heme b (iron(II)-protoporphyrin IX) group.ACTIVITY REGULATION Inhibited by p-chloromercuriphenylsulfonic acid (CMPSA).BIOPHYSICOCHEMICAL PROPERTIES Optimum pH is 6-7.SUBCELLULAR LOCATION Expressed in roots, aerial vegetative parts and reproductive organs (PubMed:14644501, Ref.1). Expressed in roots, leaves, stems and flowers (PubMed:16397796).INDUCTION By stress and hormones. By infection with rice blast fungus (M.grisea). Circadian-regulation. Expression is higher during the light phase than during the dark phase. Induced by hydrogen peroxide in leaves (PubMed:25546583).MISCELLANEOUS Binds one cation per subunit; probably K(+), but might also be Ca(2+).SIMILARITY Belongs to the peroxidase family. Ascorbate peroxidase subfamily.
created [InstanceEdit:1164949] Wu, Guanming, 2010-12-11
databaseName UniProt
dbId 1162022
description
  • recommendedName: fullName evidence="15"L-ascorbate peroxidase 1, cytosolic shortName evidence="14"APXa ecNumber evidence="9"1.11.1.11 alternativeName: fullName evidence="13"OsAPx1
displayName UniProt:Q10N21 APX1
geneName
  • APX1
  • Os03g0285700
  • LOC_Os03g17690
  • OsJ_009999
  • OSJNBa0013D02.10
identifier Q10N21
isSequenceChanged false
keyword
  • Calcium
  • Cytoplasm
  • Direct protein sequencing
  • Heme
  • Hydrogen peroxide
  • Iron
  • Metal-binding
  • Oxidoreductase
  • Peroxidase
  • Potassium
  • Reference proteome
  • Stress response
modified [InstanceEdit:9939033] Weiser, Joel, 2025-02-21
name
  • APX1
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • APX1_ORYSJ
  • B7E6Z4
  • P93404
  • Q84QS3
  • Q8GZZ2
sequenceLength 250
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/Q10N21