UniProt:Q8H8U0 Os03g0283600

chain
  • transit peptide:1-34
  • chain:35-329
checksum A6DA4DDFD45F3BFC
comment
  • FUNCTION Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG). CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions.CATALYTIC ACTIVITY a CDP-1,2-diacyl-sn-glycerol + a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) = a cardiolipin + CMP + H(+)COFACTOR Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
created [InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference
databaseName UniProt
dbId 1161987
description
  • recommendedName: fullName evidence="4"Cardiolipin synthase (CMP-forming) shortName: CLS ecNumber: 2.7.8.41
displayName UniProt:Q8H8U0 Os03g0283600
geneName
  • Os03g0283600
  • LOC_Os03g17520
identifier Q8H8U0
isSequenceChanged false
keyword
  • Lipid biosynthesis
  • Lipid metabolism
  • Membrane
  • Mitochondrion
  • Mitochondrion inner membrane
  • Phospholipid biosynthesis
  • Phospholipid metabolism
  • Reference proteome
  • Transferase
  • Transit peptide
  • Transmembrane
  • Transmembrane helix
modified [InstanceEdit:9939033] Weiser, Joel, 2025-02-21
name
  • Os03g0283600
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • CRLS1_ORYSJ
  • A0A0P0VW69
sequenceLength 329
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/Q8H8U0