UniProt:Q8H3I4 Os07g0616500

chain
  • chain:1-366
checksum 73FCBAD72CC9B9F5
comment
  • FUNCTION Oxidase that catalyzes the oxidation of a broad range of 2-hydroxyacids to the corresponding 2-oxoacids, with a reduction of O2 to H2O2. May be involved in a general medium- and long-chain fatty acid catabolic pathway such as alpha-oxidation.CATALYTIC ACTIVITY a (2S)-2-hydroxycarboxylate + O2 = a 2-oxocarboxylate + H2O2COFACTOR Lipid metabolism; fatty acid metabolism.SUBUNIT Homotetramer (By similarity). Binds to CATB and CATC; these interactions are disturbed by alpha-hydroxy-2-pyridinemethanesulfonic acid (HPMS) and salicylic acid (SA) (PubMed:26900141).SUBCELLULAR LOCATION Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
created [InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference
databaseName UniProt
dbId 1161655
description
  • recommendedName: Peroxisomal (S)-2-hydroxy-acid oxidase GLO4 ecNumber evidence="3"1.1.3.15 alternativeName: Glycolate oxidase 4 shortName: GOX 4 shortName: OsGLO4 alternativeName: Short chain alpha-hydroxy acid oxidase GLO4
displayName UniProt:Q8H3I4 Os07g0616500
geneName
  • Os07g0616500
  • GLO4
  • B1056G08.112
  • OsJ_25131
identifier Q8H3I4
isSequenceChanged false
keyword
  • Fatty acid metabolism
  • Flavoprotein
  • FMN
  • Lipid metabolism
  • Oxidoreductase
  • Peroxisome
  • Reference proteome
modified [InstanceEdit:9852000] Weiser, Joel, 2023-11-03
name
  • GLO4
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • HAOX_ORYSJ
  • A0A0P0X8U9
  • B9FU85
sequenceLength 366
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/Q8H3I4