UniProt:O64437 INO1

chain
  • chain:1-510
checksum 20DD8DFAD199F937
comment
  • FUNCTION Key enzyme in myo-inositol biosynthesis pathway that catalyzes the conversion of glucose 6-phosphate to 1-myo-inositol 1-phosphate in a NAD-dependent manner (By similarity). Is a key enzyme in the phytic acid biosynthesis pathway in seeds (PubMed:19021878).CATALYTIC ACTIVITY D-glucose 6-phosphate = 1D-myo-inositol 3-phosphateCOFACTOR Polyol metabolism; myo-inositol biosynthesis; myo-inositol from D-glucose 6-phosphate: step 1/2.SUBCELLULAR LOCATION Highly expressed in embryos, but transcripts are undetectable in roots, leaves, flowers and anthers.DEVELOPMENTAL STAGE Expressed in the apical region of globular-stage embryos 2 days after anthesis (DAA). Expressed in the scutellum and aleurone layer 4 DAA. Expression in these cells increases until 7 DAA, and then gradually decreases.INDUCTION Induced by sucrose and glucose (PubMed:11975732). Induced by abscisic acid (ABA) (PubMed:11975732, PubMed:24467907).MISCELLANEOUS Plants silencing RINO1 show a low phytic acid phenotype in seeds, and high accumulation of inorganic phosphate (Pi) in seeds.SIMILARITY Belongs to the myo-inositol 1-phosphate synthase family.
created [InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference
databaseName UniProt
dbId 1161489
description
  • recommendedName: fullName evidence="10"Inositol-3-phosphate synthase 1 shortName evidence="10"MIP synthase 1 ecNumber evidence="2"5.5.1.4 alternativeName: fullName evidence="10"Myo-inositol 1-phosphate synthase shortName evidence="10"IPS shortName evidence="10"MI-1-P synthase alternativeName: fullName evidence="8"OsINO1-1
displayName UniProt:O64437 INO1
geneName
  • INO1
  • Os03g0192700
  • LOC_Os03g09250
  • RINO1
  • INO1-1
identifier O64437
isSequenceChanged false
keyword
  • Cytoplasm
  • Inositol biosynthesis
  • Isomerase
  • Lipid biosynthesis
  • Lipid metabolism
  • NAD
  • Nucleus
  • Phospholipid biosynthesis
  • Phospholipid metabolism
  • Reference proteome
modified [InstanceEdit:9852000] Weiser, Joel, 2023-11-03
name
  • RINO1
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • RINO1_ORYSJ
  • Q10QK8
sequenceLength 510
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/O64437