UniProt:Q9LD61 PYRB

chain
  • transit peptide:1-36
  • chain:37-363
checksum F1BA00BE846A8F5D
comment
  • FUNCTION Catalyzes the condensation of carbamoyl phosphate and aspartate to form carbamoyl aspartate and inorganic phosphate, the committed step in the de novo pyrimidine nucleotide biosynthesis pathway.CATALYTIC ACTIVITY carbamoyl phosphate + L-aspartate = N-carbamoyl-L-aspartate + phosphate + H(+)ACTIVITY REGULATION Feedback inhibited by UMP.PATHWAY Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 2/3.SUBUNIT Homotrimer.SUBCELLULAR LOCATION Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
created [InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference
databaseName UniProt
dbId 1161431
description
  • recommendedName: Aspartate carbamoyltransferase, chloroplastic ecNumber evidence="1"2.1.3.2 alternativeName: Aspartate transcarbamylase shortName: ATCase
displayName UniProt:Q9LD61 PYRB
geneName
  • PYRB
  • Os08g0248800
  • LOC_Os08g15030
  • OsJ_26609
  • OSJNBa0012K14.1
  • OSJNBb0003H03.24
identifier Q9LD61
isSequenceChanged false
keyword
  • Allosteric enzyme
  • Chloroplast
  • Plastid
  • Pyrimidine biosynthesis
  • Reference proteome
  • Transferase
  • Transit peptide
modified [InstanceEdit:9939033] Weiser, Joel, 2025-02-21
name
  • PYRB
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • PYRB_ORYSJ
  • A0A0N7KPI9
sequenceLength 363
species [Species:186860] Oryza sativa
url http://purl.uniprot.org/uniprot/Q9LD61