UniProt:Q7XUS2 ASB1

chain
  • transit peptide:1-58
  • chain:59-288
checksum B4400C836A3FD366
comment
  • FUNCTION Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS to produce anthranilate.CATALYTIC ACTIVITY chorismate + L-glutamine = anthranilate + pyruvate + L-glutamate + H(+)BIOPHYSICOCHEMICAL PROPERTIES kcat is 34.7 sec(-1) with chorismate as substrate (for recombinant ASA1 and ASB1 proteins synthesized with the wheat germ cell-free system). kcat is 14.6 sec(-1) with chorismate as substrate (for recombinant ASA2 and ASB1 proteins synthesized with the wheat germ cell-free system).PATHWAY Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 1/5.SUBUNIT Heterotetramer consisting of two non-identical subunits: a beta subunit and a large alpha subunit.SUBCELLULAR LOCATION Expressed in roots and leaves.INDUCTION By the phytopathogenic fungus Bipolaris oryzae.
created [InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference
databaseName UniProt
dbId 1160030
description
  • recommendedName: fullName evidence="7"Anthranilate synthase beta subunit 1, chloroplastic shortName evidence="7"OsASB1 ecNumber evidence="5"4.1.3.27 alternativeName: Anthranilate synthase, glutamine amidotransferase component 2-1
displayName UniProt:Q7XUS2 ASB1
geneName
  • ASB1
  • OASB1
  • Os04g0463500
  • LOC_Os04g38950
  • B1358B12.20
  • OSJNBa0060P14.1
identifier Q7XUS2
isSequenceChanged false
keyword
  • Amino-acid biosynthesis
  • Aromatic amino acid biosynthesis
  • Chloroplast
  • Glutamine amidotransferase
  • Lyase
  • Plastid
  • Reference proteome
  • Transit peptide
  • Tryptophan biosynthesis
modified [InstanceEdit:9939033] Weiser, Joel, 2025-02-21
name
  • ASB1
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • ASB1_ORYSJ
  • A0A0P0WBC9
sequenceLength 288
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/Q7XUS2