UniProt:Q0JF02 CPS4

chain
  • transit peptide:1-47
  • chain:48-767
checksum 436367D7CAE2FF42
comment
  • FUNCTION Catalyzes the conversion of geranylgeranyl diphosphate to the phytoalexin precursor syn-copalyl diphosphate (PubMed:15255861, PubMed:15341631, PubMed:23621683). Required for the biosynthesis of momilactones that exude from roots and act as allelochemicals against lowland weeds in paddy soil (PubMed:23621683).CATALYTIC ACTIVITY (2E,6E,10E)-geranylgeranyl diphosphate = 9alpha-copalyl diphosphateCOFACTOR Induced by UV irradiation (PubMed:15255861, PubMed:15341631). Induced by methyl jasmonate (PubMed:15255861).DOMAIN The Asp-Xaa-Asp-Asp (DXDD) motif is important for the catalytic activity, presumably through binding to Mg(2+).DISRUPTION PHENOTYPE No visible phenotype under normal growth conditions (PubMed:23621683). Mutant plants exhibit increased susceptibility to the rice blast fungus Magnaporthe grisea, and reduced capacity to inhibit germination and growth of lowland weeds in paddy soil, possibly due to decreased levels of momilactones and oryzalexin S (PubMed:23621683).MISCELLANEOUS Phytoalexins are diterpenoid secondary metabolites involved in the defense mechanism of the plant and produced in response to attack (by a pathogen, elicitor or UV irradiation).SIMILARITY Belongs to the terpene synthase family.
created [InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference
databaseName UniProt
dbId 1159894
description
  • recommendedName: fullName evidence="10"Syn-copalyl diphosphate synthase, chloroplastic shortName evidence="9"OsCPSsyn shortName evidence="9"Syn-CPP synthase ecNumber evidence="5 6"5.5.1.14 alternativeName: fullName evidence="11"OsCPS4 alternativeName: fullName evidence="10"OsCyc1
displayName UniProt:Q0JF02 CPS4
geneName
  • CPS4
  • CYC1
  • Os04g0178300
  • LOC_Os04g09900
  • OSJNBa0096F01.12
identifier Q0JF02
isSequenceChanged false
keyword
  • 3D-structure
  • Alternative splicing
  • Chloroplast
  • Isomerase
  • Magnesium
  • Metal-binding
  • Plant defense
  • Plastid
  • Reference proteome
  • Transit peptide
modified [InstanceEdit:9917590] Weiser, Joel, 2024-08-09
name
  • CPS4
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • CPS4_ORYSJ
  • Q68CM0
  • Q7XNG1
sequenceLength 767
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/Q0JF02