UniProt:Q8LIY8 CCD8B

chain
  • transit peptide:1-43
  • chain:44-569
checksum AE4E1A0327AEF869
comment
  • FUNCTION Involved in strigolactones biosynthesis by cleaving the C(27) 9-cis-10'-apo-beta-carotenal produced by CCD7. Produces the C(19) carlactone and a C(8) hydroxyaldehyde. Also shows lower activity with all-trans-10'-apo-beta-carotenal producing a C(9) dialdehyde and the C(18) 13-apo-beta-carotenone. Strigolactones are hormones that inhibit tillering and shoot branching through the MAX-dependent pathway, contribute to the regulation of shoot architectural response to phosphate-limiting conditions and function as rhizosphere signal that stimulates hyphal branching of arbuscular mycorrhizal fungi and trigger seed germination of root parasitic weeds.CATALYTIC ACTIVITY 9-cis-10'-apo-beta-carotenal + 2 O2 = (2E,4E,6E)-7-hydroxy-4-methylhepta-2,4,6-trienal + (11R)-carlactoneCATALYTIC ACTIVITY all-trans-10'-apo-beta-carotenal + O2 = (2E,4E,6E)-4-methylocta-2,4,6-trienedial + 13-apo-beta-carotenoneCOFACTOR Binds 1 Fe(2+) ion per subunit.SUBCELLULAR LOCATION Expressed in parenchyma cells of the root stele, shoot apex, leaf buds, xylem parenchyma cells of the stem, inflorescences and panicles.INDUCTION By auxin.DISRUPTION PHENOTYPE Dwarf phenotype with increased branching and tiller number, and strong reduction of the root levels of strigolactones.MISCELLANEOUS The branching phenotypes of the ccd7/max3 and ccd8b/max4 mutants can be rescued by exogenous treatment with the synthetic strigolactone analogs GR24 and 4BD.SIMILARITY Belongs to the carotenoid oxygenase family.
created [InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference
databaseName UniProt
dbId 1159560
description
  • recommendedName: Carotenoid cleavage dioxygenase 8 homolog B, chloroplastic shortName: OsCCD8b ecNumber evidence="9"1.13.11.69 ecNumber evidence="6"1.13.11.70 alternativeName: Protein DWARF-10 alternativeName: Protein MAX4 homolog
displayName UniProt:Q8LIY8 CCD8B
geneName
  • CCD8B
  • D10
  • Os01g0746400
  • LOC_Os01g54270
  • OSJNBa0014K08.38
identifier Q8LIY8
isSequenceChanged false
keyword
  • Chloroplast
  • Dioxygenase
  • Iron
  • Metal-binding
  • Oxidoreductase
  • Plastid
  • Reference proteome
  • Transit peptide
modified [InstanceEdit:9939033] Weiser, Joel, 2025-02-21
name
  • CCD8B
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • CCD8B_ORYSJ
  • A0A0P0V860
  • Q0JJD5
sequenceLength 569
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/Q8LIY8