UniProt:Q8W250 DXR

chain
  • transit peptide:1-49
  • chain:50-473
checksum 9933D9D8C3D1FC49
comment
  • FUNCTION Enzyme of the plastid non-mevalonate pathway for isoprenoid biosynthesis that catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP). Required for chloroplast development.CATALYTIC ACTIVITY 2-C-methyl-D-erythritol 4-phosphate + NADP(+) = 1-deoxy-D-xylulose 5-phosphate + NADPH + H(+)COFACTOR Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 1/6.SUBCELLULAR LOCATION By the mycorrhizal fungus G.intraradices colonization in roots.SIMILARITY Belongs to the DXR family.
created [InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference
databaseName UniProt
dbId 1158936
description
  • recommendedName: 1-deoxy-D-xylulose 5-phosphate reductoisomerase, chloroplastic shortName: 1-deoxyxylulose-5-phosphate reductoisomerase shortName: DXP reductoisomerase ecNumber evidence="2"1.1.1.267 alternativeName: 2-C-methyl-D-erythritol 4-phosphate synthase
displayName UniProt:Q8W250 DXR
geneName
  • DXR
  • Os01g0106900
  • LOC_Os01g01710
  • OsJ_00058
  • P0005A05.24
  • P0482C06.2
identifier Q8W250
isSequenceChanged false
keyword
  • Chloroplast
  • Isoprene biosynthesis
  • Manganese
  • Metal-binding
  • NADP
  • Oxidoreductase
  • Plastid
  • Reference proteome
  • Transit peptide
modified [InstanceEdit:9939033] Weiser, Joel, 2025-02-21
name
  • DXR
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • DXR_ORYSJ
  • A0A0N7KC68
  • Q0JRD4
  • Q9FTN0
sequenceLength 473
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/Q8W250