UniProt:Q0JEZ8 KSL4

chain
  • transit peptide:1-56
  • chain:57-842
checksum B533670CF93D8835
comment
  • FUNCTION Involved in the biosynthesis of momilactone A and B phytoalexins. Catalyzes the conversion of syn-copalyl diphosphate to the phytoalexin precursor syn-pimara-7,15-diene.CATALYTIC ACTIVITY 9alpha-copalyl diphosphate = 9beta-pimara-7,15-diene + diphosphateCOFACTOR Binds 3 Mg(2+) ions per subunit.SUBCELLULAR LOCATION Expressed in roots.DEVELOPMENTAL STAGE Expressed from 2 to 6 days after seed imbibition.INDUCTION Induced by UV irradiation.DOMAIN The Asp-Asp-Xaa-Xaa-Asp/Glu (DDXXD/E) motif is important for the catalytic activity, presumably through binding to Mg(2+).MISCELLANEOUS 9-beta-pimara-7,15-diene is a precursor of the phytoalexins momilactones A and B. Phytoalexins are diterpenoid secondary metabolites involved in the defense mechanism of the plant and produced in response to attack (by a pathogen, elicitor or UV irradiation). Momilactone B can also act as an allochemical (an antimicrobial and allelopathic agent), being constitutively produced in the root of the plant and secreted to the rhizosphere where it suppresses the growth of neighboring plants and soil microorganisms.SIMILARITY Belongs to the terpene synthase family.
created [InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference
databaseName UniProt
dbId 1158522
description
  • recommendedName: fullName evidence="6"9-beta-pimara-7,15-diene synthase, chloroplastic ecNumber evidence="3 5"4.2.3.35 alternativeName: fullName evidence="7"Ent-kaurene synthase-like 4 shortName evidence="6"OsKS4 shortName evidence="7"OsKSL4 alternativeName: fullName evidence="8"OsDTS2 alternativeName: fullName evidence="7"Syn-pimara-7,15-diene synthase
displayName UniProt:Q0JEZ8 KSL4
geneName
  • KSL4
  • DTS2
  • KS4
  • Os04g0179700
  • LOC_Os04g10060
  • OsJ_013413
  • OSJNBa0052P16.14
identifier Q0JEZ8
isSequenceChanged false
keyword
  • Chloroplast
  • Lyase
  • Magnesium
  • Metal-binding
  • Plant defense
  • Plastid
  • Reference proteome
  • Transit peptide
modified [InstanceEdit:9852000] Weiser, Joel, 2023-11-03
name
  • KSL4
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • KSL4_ORYSJ
  • A0A0N7KIL5
  • Q60HB5
  • Q69DS7
  • Q7XX63
sequenceLength 842
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/Q0JEZ8