UniProt:Q8S2G0 ISPE

chain
  • transit peptide:1-52
  • chain:53-401
checksum 23A259FF4DDCF320
comment
  • FUNCTION Enzyme of the plastid non-mevalonate pathway for isoprenoid biosynthesis that catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. Is essential for chloroplast development (By similarity).CATALYTIC ACTIVITY 4-CDP-2-C-methyl-D-erythritol + ATP = 4-CDP-2-C-methyl-D-erythritol 2-phosphate + ADP + H(+)PATHWAY Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 3/6.SUBCELLULAR LOCATION Belongs to the GHMP kinase family. IspE subfamily.
created [InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference
databaseName UniProt
dbId 1158143
description
  • recommendedName: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, chloroplastic ecNumber: 2.7.1.148 alternativeName: 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase shortName: CDPMEK shortName: CMEK
displayName UniProt:Q8S2G0 ISPE
geneName
  • ISPE
  • Os01g0802100
  • LOC_Os01g58790
  • OsJ_01815
  • P0003D09.29
identifier Q8S2G0
isSequenceChanged false
keyword
  • ATP-binding
  • Chloroplast
  • Isoprene biosynthesis
  • Kinase
  • Nucleotide-binding
  • Plastid
  • Reference proteome
  • Transferase
  • Transit peptide
modified [InstanceEdit:9852000] Weiser, Joel, 2023-11-03
name
  • ISPE
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • ISPE_ORYSJ
  • A0A0P0V9H3
sequenceLength 401
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/Q8S2G0