UniProt:Q7F0Q2 Os07g0493400

chain
  • chain:1-353
checksum 08E6F432E2DCE6C0
comment
  • FUNCTION Plays a key role in early steps of protein N-linked glycosylation by being involved in the conversion of polyprenol into dolichol (By similarity). Acts as a polyprenal reductase that mediates the reduction of polyprenal into dolichal in a NADP-dependent mechanism (By similarity). Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-glycosylation (By similarity).CATALYTIC ACTIVITY a di-trans,poly-cis-dolichal + NADP(+) = a di-trans,poly-cis-polyprenal + NADPH + H(+)PATHWAY Protein modification; protein glycosylation.SUBCELLULAR LOCATION Belongs to the steroid 5-alpha reductase family. Polyprenal reductase subfamily.
created [InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference
databaseName UniProt
dbId 1157967
description
  • recommendedName: fullName evidence="4"Polyprenal reductase 2 ecNumber evidence="2"1.3.1.94
displayName UniProt:Q7F0Q2 Os07g0493400
geneName
  • Os07g0493400
  • LOC_Os07g31140
  • OsJ_24314
  • P0038F10.126
identifier Q7F0Q2
isSequenceChanged false
keyword
  • Cell membrane
  • Membrane
  • NADP
  • Oxidoreductase
  • Reference proteome
  • Transmembrane
  • Transmembrane helix
modified [InstanceEdit:9939033] Weiser, Joel, 2025-02-21
name
  • Os07g0493400
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • PPRD2_ORYSJ
  • A0A0P0X626
sequenceLength 353
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/Q7F0Q2