UniProt:Q6K2E8 ALS1

chain
  • transit peptide:1-43
  • chain:44-644
checksum ED626E55F8B89EC9
comment
  • CATALYTIC ACTIVITY 2 pyruvate + H(+) = (2S)-2-acetolactate + CO2COFACTOR Binds 1 Mg(2+) ion per subunit.COFACTOR Binds 1 thiamine pyrophosphate per subunit.PATHWAY Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 1/4.PATHWAY Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 1/4.SUBCELLULAR LOCATION Acetolactate synthase is the target enzyme for sulfonylurea and imidazolinone herbicides.SIMILARITY Belongs to the TPP enzyme family.
created [InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference
databaseName UniProt
dbId 1157858
description
  • recommendedName: Acetolactate synthase 1, chloroplastic ecNumber: 2.2.1.6 alternativeName: Acetohydroxy-acid synthase 1
displayName UniProt:Q6K2E8 ALS1
geneName
  • ALS1
  • Os02g0510200
  • LOC_Os02g30630
  • OSJNBa0052M16.38
identifier Q6K2E8
isSequenceChanged false
keyword
  • Amino-acid biosynthesis
  • Branched-chain amino acid biosynthesis
  • Chloroplast
  • Disulfide bond
  • FAD
  • Flavoprotein
  • Herbicide resistance
  • Magnesium
  • Metal-binding
  • Plastid
  • Reference proteome
  • Thiamine pyrophosphate
  • Transferase
  • Transit peptide
modified [InstanceEdit:9939033] Weiser, Joel, 2025-02-21
name
  • ALS1
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • ILVB1_ORYSJ
  • Q5D6B1
  • Q5D6B2
  • Q5D6B3
  • Q9FRV2
  • Q9FRV3
sequenceLength 644
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/Q6K2E8