UniProt:Q2QQJ5 KSL10

chain
  • transit peptide:1-38
  • chain:39-815
checksum F483899E55ACA15D
comment
  • FUNCTION Involved in the biosynthesis of oryzalexin A-F phytoalexins. Catalyzes the conversion of ent-copalyl diphosphate to the phytoalexin precursor ent-sandaracopimaradiene.CATALYTIC ACTIVITY ent-copalyl diphosphate = ent-sandaracopimara-8(14),15-diene + diphosphateCATALYTIC ACTIVITY 9alpha-copalyl diphosphate = (12E)-9alpha-labda-8(17),12,14-triene + diphosphateCOFACTOR Binds 3 Mg(2+) ions per subunit.BIOPHYSICOCHEMICAL PROPERTIES Induced by UV irradiation.DOMAIN The Asp-Asp-Xaa-Xaa-Asp/Glu (DDXXD/E) motif is important for the catalytic activity, presumably through binding to Mg(2+).MISCELLANEOUS ent-sandaracopimaradiene is a precursor of the phytoalexins oryzalexins A-F. Phytoalexins are diterpenoid secondary metabolites involved in the defense mechanism of the plant and produced in response to attack (by a pathogen, elicitor or UV irradiation).SIMILARITY Belongs to the terpene synthase family.
created [InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference
databaseName UniProt
dbId 1157525
description
  • recommendedName: fullName evidence="7"Ent-sandaracopimara-8(14),15-diene synthase, chloroplastic ecNumber evidence="3 6"4.2.3.29 alternativeName: fullName evidence="8"Ent-kaurene synthase-like 10 shortName evidence="8"OsKSL10 alternativeName: fullName evidence="7"Ent-sandaracopimaradiene synthase alternativeName: fullName evidence="9"Labdatriene synthase ecNumber evidence="6"4.2.3.99
displayName UniProt:Q2QQJ5 KSL10
geneName
  • KSL10
  • KS10
  • Os12g0491800
  • LOC_Os12g30824
identifier Q2QQJ5
isSequenceChanged false
keyword
  • Chloroplast
  • Lyase
  • Magnesium
  • Metal-binding
  • Plant defense
  • Plastid
  • Reference proteome
  • Transit peptide
modified [InstanceEdit:9939033] Weiser, Joel, 2025-02-21
name
  • KSL10
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • KSL10_ORYSJ
  • A0A0P0YAB2
  • Q00G36
  • Q60HB4
sequenceLength 815
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/Q2QQJ5