UniProt:Q6ZJJ1 APX4

chain
  • chain:1-291
checksum 5B605C442EB57807
comment
  • FUNCTION Plays a key role in hydrogen peroxide removal.CATALYTIC ACTIVITY L-ascorbate + H2O2 = L-dehydroascorbate + 2 H2OCOFACTOR Binds 1 heme b (iron(II)-protoporphyrin IX) group.SUBCELLULAR LOCATION Expressed in leaves, stems and flowers.INDUCTION Down-regulated by hydrogen peroxide in leaves.MISCELLANEOUS Binds one cation per subunit; probably K(+), but might also be Ca(2+).SIMILARITY Belongs to the peroxidase family. Ascorbate peroxidase subfamily.CAUTION According to PubMed:15599508, it may be peroxisomal. There is however no experimental evidence to prove this.
created [InstanceEdit:1164949] Wu, Guanming, 2010-12-11
databaseName UniProt
dbId 1157513
description
  • recommendedName: fullName evidence="9"Probable L-ascorbate peroxidase 4, peroxisomal ecNumber evidence="9"1.11.1.11 alternativeName: fullName evidence="8"OsAPx4
displayName UniProt:Q6ZJJ1 APX4
geneName
  • APX4
  • Os08g0549100
  • LOC_Os08g43560
  • OJ1479_B11.9
identifier Q6ZJJ1
isSequenceChanged false
keyword
  • Calcium
  • Heme
  • Hydrogen peroxide
  • Iron
  • Membrane
  • Metal-binding
  • Oxidoreductase
  • Peroxidase
  • Peroxisome
  • Potassium
  • Reference proteome
  • Transmembrane
  • Transmembrane helix
modified [InstanceEdit:9939033] Weiser, Joel, 2025-02-21
name
  • APX4
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • APX4_ORYSJ
  • Q0J3W2
sequenceLength 291
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/Q6ZJJ1