UniProt:Q8LGZ9 GA2OX5

chain
  • chain:1-341
checksum DCB91809DFEE99B3
comment
  • FUNCTION Catalyzes the 2-beta-hydroxylation of several biologically active gibberellins (GAs), leading to the homeostatic regulation of their endogenous level (PubMed:18952778, PubMed:24475234). Catabolism of GAs plays a central role in plant development (PubMed:18952778, PubMed:24475234). In vitro, converts GA12 and GA53 to the corresponding 2-beta-hydroxylated products GA110 and GA97, respectively (PubMed:18952778).CATALYTIC ACTIVITY gibberellin A1 + 2-oxoglutarate + O2 = gibberellin A8 + succinate + CO2COFACTOR Binds 1 Fe(2+) ion per subunit.PATHWAY Plant hormone biosynthesis; gibberellin biosynthesis.SUBCELLULAR LOCATION Expressed in roots, leaves, culms, leaf sheaths and young panicles.MISCELLANEOUS Plant overexpressing GA2OX5 exhibit an extremely dwarf phenotype.SIMILARITY Belongs to the iron/ascorbate-dependent oxidoreductase family. GA2OX subfamily.
created [InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference
databaseName UniProt
dbId 1157441
description
  • recommendedName: fullName evidence="6"Gibberellin 2-beta-dioxygenase 5 ecNumber evidence="7"1.14.11.13 alternativeName: fullName evidence="6"Gibberellin 2-beta-hydroxylase 5 alternativeName: fullName evidence="5"Gibberellin 2-oxidase 5 shortName evidence="5"GA 2-oxidase 5 shortName evidence="5"OsGA2ox5
displayName UniProt:Q8LGZ9 GA2OX5
geneName
  • GA2OX5
  • Os07g0103500
  • LOC_Os07g01340
  • P0446F04.116
identifier Q8LGZ9
isSequenceChanged false
keyword
  • Cytoplasm
  • Dioxygenase
  • Iron
  • Metal-binding
  • Nucleus
  • Oxidoreductase
  • Reference proteome
modified [InstanceEdit:9939033] Weiser, Joel, 2025-02-21
name
  • GA2OX5
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • G2OX5_ORYSJ
sequenceLength 341
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/Q8LGZ9