UniProt:Q5VRM7 KAO

chain
  • chain:1-506
checksum AE3B82D95633A502
comment
  • FUNCTION Involved in gibberellin (GA) biosynthesis. Catalyzes three successive oxidations of ent-kaurenoic acid giving gibberellin 12 (GA12), a key step in GAs biosynthesis. GAs, which are involved many processes, including stem elongation, play a central role in plant development (Probable). Required for pollen germination and elongation (PubMed:18083909).CATALYTIC ACTIVITY ent-kaur-16-en-19-oate + 3 reduced [NADPH--hemoprotein reductase] + 3 O2 = gibberellin A12 + 3 oxidized [NADPH--hemoprotein reductase] + 4 H2O + 4 H(+)COFACTOR Plant hormone biosynthesis; gibberellin biosynthesis.SUBCELLULAR LOCATION Expressed in roots and panicles. Expressed at low levels in vegetative shoot apices, leaf sheaths, leaf blades and stems.DISRUPTION PHENOTYPE Severe dwarf phenotype without flower or seed development.SIMILARITY Belongs to the cytochrome P450 family.
created [InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference
databaseName UniProt
dbId 1156452
description
  • recommendedName: fullName evidence="8"Ent-kaurenoic acid oxidase shortName evidence="6"OsKAO ecNumber evidence="1"1.14.14.107 alternativeName: fullName evidence="8"Cytochrome P450 88A5 alternativeName: fullName evidence="7"Protein REDUCED POLLEN ELONGATION 1
displayName UniProt:Q5VRM7 KAO
geneName
  • KAO
  • CYP88A5
  • RPE1
  • Os06g0110000
  • LOC_Os06g02019
  • OSJNBa0004I20.18
  • P0514G12.42
identifier Q5VRM7
isSequenceChanged false
keyword
  • Endoplasmic reticulum
  • Heme
  • Iron
  • Membrane
  • Metal-binding
  • Monooxygenase
  • Oxidoreductase
  • Reference proteome
  • Transmembrane
  • Transmembrane helix
modified [InstanceEdit:9939033] Weiser, Joel, 2025-02-21
name
  • KAO
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • KAO_ORYSJ
  • D0PQ37
sequenceLength 506
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/Q5VRM7