UniProt:Q337F3 LOC_OS10G35940

comment
  • FUNCTION: Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis (By similarity).
  • CATALYTIC ACTIVITY: ATP + tetrahydropteroyl-(gamma-Glu)(n) + L- glutamate = ADP + phosphate + tetrahydropteroyl-(gamma-Glu)(n+1).
  • COFACTOR: A monovalent cation (By similarity).
  • PATHWAY: Cofactor biosynthesis; tetrahydrofolylpolyglutamate biosynthesis.
created [InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference
databaseName UniProt
dbId 1155598
displayName UniProt:Q337F3 LOC_OS10G35940
geneName
  • LOC_OS10G35940
  • Os10g0503200
  • LOC_Os10g35940
identifier Q337F3
keyword
  • Complete proteome
  • Ligase
  • One-carbon metabolism
modified [InstanceEdit:2871188] D'Eustachio, P, 2012-12-20
name
  • folylpolyglutamate synthetase, putative, expressed//tetrahydrofolylpolyglutamate synthase
  • protein6686
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • Q337F3_ORYSJ
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/Q337F3