UniProt:P14717 PAL

chain
  • chain:1-701
checksum C6AA7CB8DB4F8EE0
comment
  • FUNCTION This is a key enzyme of plant metabolism catalyzing the first reaction in the biosynthesis from L-phenylalanine of a wide variety of natural products based on the phenylpropane skeleton.CATALYTIC ACTIVITY L-phenylalanine = (E)-cinnamate + NH4(+)PATHWAY Phenylpropanoid metabolism; trans-cinnamate biosynthesis; trans-cinnamate from L-phenylalanine: step 1/1.SUBUNIT Homotetramer.SUBCELLULAR LOCATION Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.SIMILARITY Belongs to the PAL/histidase family.
created [InstanceEdit:1164949] Wu, Guanming, 2010-12-11
databaseName UniProt
dbId 1155022
description
  • recommendedName: Phenylalanine ammonia-lyase ecNumber evidence="2"4.3.1.24
displayName UniProt:P14717 PAL
geneName
  • PAL
  • Os02g0626100
  • LOC_Os02g41630
  • B1215B07.42
  • OsJ_07592
  • P0042D01.1
identifier P14717
isSequenceChanged false
keyword
  • Cytoplasm
  • Direct protein sequencing
  • Lyase
  • Phenylalanine catabolism
  • Phenylpropanoid metabolism
  • Reference proteome
modified [InstanceEdit:9852000] Weiser, Joel, 2023-11-03
name
  • PAL
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • PAL1_ORYSJ
  • Q0DZE3
  • Q6K1Q8
sequenceLength 701
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/P14717