UniProt:Q7FAH2 GAPC2

chain
  • chain:1-337
checksum 6B410B6AB2D068A8
comment
  • FUNCTION Key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Essential for the maintenance of cellular ATP levels and carbohydrate metabolism (By similarity).CATALYTIC ACTIVITY D-glyceraldehyde 3-phosphate + phosphate + NAD(+) = (2R)-3-phospho-glyceroyl phosphate + NADH + H(+)PATHWAY Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 1/5.SUBUNIT Homotetramer.SUBCELLULAR LOCATION S-nitrosylated upon accumulation of NO in plants.MISCELLANEOUS Plants contain two types of GAPDH: cytosolic forms which participate in glycolysis and chloroplast forms which participate in photosynthesis. All the forms are encoded by distinct genes.SIMILARITY Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
created [InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference
databaseName UniProt
dbId 1155009
description
  • recommendedName: Glyceraldehyde-3-phosphate dehydrogenase 2, cytosolic ecNumber: 1.2.1.12
displayName UniProt:Q7FAH2 GAPC2
geneName
  • GAPC2
  • GAPDH
  • Os04g0486600
  • LOC_Os04g40950
  • H0302E05.3
  • OJ000223_09.15
identifier Q7FAH2
isSequenceChanged false
keyword
  • Cytoplasm
  • Glycolysis
  • NAD
  • Oxidoreductase
  • Reference proteome
  • S-nitrosylation
modified [InstanceEdit:9939033] Weiser, Joel, 2025-02-21
name
  • GAPC2
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • G3PC2_ORYSJ
  • A0A0P0WBU1
  • J3JRU7
sequenceLength 337
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/Q7FAH2