UniProt:Q7XHL3 TDC2

chain
  • chain:1-497
checksum D65FB31F5E8D05A4
comment
  • FUNCTION Involved in serotonin biosynthesis. Catalyzes the decarboxylation of L-tryptophan to tryptamine, which is converted to serotonin by tryptamine 5-hydroxylase (PubMed:17763868). May play a minor role in serotonin biosynthetis during senescence. Accumulation of serotonin attenuates leaf senescence (PubMed:19439571).CATALYTIC ACTIVITY L-tryptophan + H(+) = tryptamine + CO2COFACTOR Belongs to the group II decarboxylase family.
created [InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference
databaseName UniProt
dbId 1155008
description
  • recommendedName: fullName evidence="4"Tryptophan decarboxylase 2 ecNumber evidence="2"4.1.1.-
displayName UniProt:Q7XHL3 TDC2
geneName
  • TDC2
  • Os07g0437500
  • LOC_Os07g25590
  • OSJNBa0026I22.3
  • OSJNBb0095H08.30
identifier Q7XHL3
isSequenceChanged false
keyword
  • Decarboxylase
  • Lyase
  • Pyridoxal phosphate
  • Reference proteome
  • Serotonin biosynthesis
modified [InstanceEdit:9939033] Weiser, Joel, 2025-02-21
name
  • TDC2
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • TDC2_ORYSJ
  • Q0D6V0
sequenceLength 497
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/Q7XHL3