UniProt:P15280 AGPS2

chain
  • transit peptide:1-64
  • chain:65-514
checksum 821C1931321C7E52
comment
  • FUNCTION Involved in synthesis of starch. Catalyzes the synthesis of ADP-glucose, a molecule that serves as an activated glycosyl donor for alpha-1,4-glucan synthesis. The chloroplastic isoform 1 is essential for starch synthesis in leaf chloroplasts and the cytosolic isoform 2 for synthesis in seed endosperm.CATALYTIC ACTIVITY alpha-D-glucose 1-phosphate + ATP + H(+) = ADP-alpha-D-glucose + diphosphateACTIVITY REGULATION Activated by 3'phosphoglycerate, inhibited by orthophosphate. Allosteric regulation. Inhibited by inorganic phosphate (Pi).PATHWAY Glycan biosynthesis; starch biosynthesis.SUBUNIT Heterotetramer composed of two small and two large subunits.SUBCELLULAR LOCATION Found in the chloroplast in leaf. Found in the plastid in the developing endosperm.SUBCELLULAR LOCATION Expressed in leaves.DEVELOPMENTAL STAGE Expressed in developing seeds from 1 to 15 days after flowering (DAF).DISRUPTION PHENOTYPE Shrunken seed endosperm due to a strong reduction in starch synthesis.SIMILARITY Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
created [InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference
databaseName UniProt
dbId 1154918
description
  • recommendedName: fullName evidence="12"Glucose-1-phosphate adenylyltransferase small subunit 2, chloroplastic/amyloplastic/cytosolic shortName evidence="8"OsAGPS2 shortName evidence="7"OsAPS2 ecNumber evidence="5"2.7.7.27 alternativeName: fullName evidence="12"ADP-glucose pyrophosphorylase AGPS2 alternativeName: fullName evidence="12"ADP-glucose synthase AGPS2 alternativeName: AGPase B alternativeName: Alpha-D-glucose-1-phosphate adenyl transferase alternativeName: fullName evidence="8"OsAGPS2a alternativeName: fullName evidence="8"OsAGPS2b
displayName UniProt:P15280 AGPS2
geneName
  • AGPS2
  • APS2
  • Os08g0345800
  • LOC_Os08g25734
  • OsJ_26991
  • P0410E11.123-1
  • P0410E11.123-2
identifier P15280
isSequenceChanged false
keyword
  • Allosteric enzyme
  • Alternative splicing
  • Amyloplast
  • ATP-binding
  • Chloroplast
  • Cytoplasm
  • Nucleotide-binding
  • Nucleotidyltransferase
  • Plastid
  • Reference proteome
  • Starch biosynthesis
  • Transferase
  • Transit peptide
modified [InstanceEdit:9852000] Weiser, Joel, 2023-11-03
name
  • AGPS2
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • GLGS2_ORYSJ
  • A3BS75
  • A8ASG3
  • Q0J698
  • Q7EZW3
  • Q84QT8
  • Q94JM6
sequenceLength 514
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/P15280