UniProt:Q10QR9 UROS

chain
  • transit peptide:1-50
  • chain:51-302
checksum E9964659A861998B
comment
  • FUNCTION Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III, a precursor of tetrapyrroles such as chlorophyll, heme and phycobilins.CATALYTIC ACTIVITY hydroxymethylbilane = uroporphyrinogen III + H2OPATHWAY Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 3/4.SUBCELLULAR LOCATION Belongs to the uroporphyrinogen-III synthase family.
created [InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference
databaseName UniProt
dbId 1154912
description
  • recommendedName: Uroporphyrinogen-III synthase, chloroplastic ecNumber: 4.2.1.75 alternativeName: Hydroxymethylbilane hydrolyase [cyclizing] alternativeName: Uroporphyrinogen-III cosynthase
displayName UniProt:Q10QR9 UROS
geneName
  • UROS
  • HEMD
  • Os03g0186100
  • LOC_Os03g08730
identifier Q10QR9
isSequenceChanged false
keyword
  • Chlorophyll biosynthesis
  • Chloroplast
  • Lyase
  • Plastid
  • Porphyrin biosynthesis
  • Reference proteome
  • Transit peptide
modified [InstanceEdit:9939033] Weiser, Joel, 2025-02-21
name
  • UROS
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • HEM4_ORYSJ
  • A0A0P0VU16
sequenceLength 302
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/Q10QR9