UniProt:O24174 Os04g0464200

chain
  • chain:1-505
checksum 85EFA42B059A8081
comment
  • FUNCTION Dehydrogenase that can use N-acetyl-gamma-aminobutyraldehyde (NAGABald), gamma-guanidinobutyraldehyde (GGBald), betaine aldehyde (Bet-ald), gamma-aminobutyraldehyde (GAB-ald), acetaldehyde, 4-aminobutylaldehyde (AB-ald), 3-aminopropionaldehyde (AP-ald), 4-N-trimethylaminobutyraldehyde (TMAB-ald) and 3-N-trimethylaminopropionaldehyde (TMAP-ald) as substrates. Catalyzes the oxidation of GAB-ald more efficiently than Bet-ald. May convert acetaldehyde into acetate, thus facilitating the production of acetyl-CoA in peroxisomes under anaerobic conditions.CATALYTIC ACTIVITY betaine aldehyde + NAD(+) + H2O = glycine betaine + NADH + 2 H(+)BIOPHYSICOCHEMICAL PROPERTIES Optimum pH is 9.5.PATHWAY Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine from betaine aldehyde: step 1/1.SUBUNIT Homodimer.SUBCELLULAR LOCATION Following submergence treatment, transient decreased levels that recovers after re-aeration.SIMILARITY Belongs to the aldehyde dehydrogenase family.
created [InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference
databaseName UniProt
dbId 1154847
description
  • recommendedName: Betaine aldehyde dehydrogenase 1 shortName: OsBADH1 ecNumber: 1.2.1.8
displayName UniProt:O24174 Os04g0464200
geneName
  • Os04g0464200
  • LOC_Os04g39020
  • BADH1
  • OSJNBa0060P14.8
identifier O24174
isSequenceChanged false
keyword
  • NAD
  • Oxidoreductase
  • Peroxisome
  • Reference proteome
modified [InstanceEdit:9939033] Weiser, Joel, 2025-02-21
name
  • BADH1
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • BADH1_ORYSJ
  • Q0JCK7
  • Q7F9Q3
sequenceLength 505
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/O24174