The gene Os05g0438800 in rice (Oryza sativa) encodes an actin-like protein involved in the plant?s response to various environmental stresses. Specifically, this gene regulates hypoxia tolerance and germination under low-oxygen conditions (Yuan et al., 2024). Actin protein is an essential component of the cytoskeleton; it plays a vital role in cytoplasmic streaming, cell shape determination, cell division, organelle movement, and extension growth. Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Essential component of cell cytoskeleton; plays an important role in cytoplasmic streaming, cell shape determination, cell division, organelle movement and extension growth.