HAC1;1

Stable Identifier
R-OSA-9618057
Type
Protein [EntityWithAccessionedSequence]
Species
Oryza sativa
Synonyms
High As Content, As(V) reductase
Locations in the PathwayBrowser
Expand all
Summation

OsHAC1;1 and OsHAC1;2 encode arsenate reductase which reduces arsenate to arsenite. OsHAC1:1 and OsHAC1;2 are predominantly expressed in roots, with OsHAC1;1 being abundant in the epidermis, root hairs, and pericycle cells while OsHAC1;2 is abundant in the epidermis, outer layers of cortex, and endodermis cells. Expression of both the genes is induced by arsenate exposure. Knocking out OsHAC1;1 or OsHAC1;2 decreases the reduction of arsenate to arsenite in roots, reducing arsenite efflux to the external medium. Loss of arsenite efflux is also associated with increased As accumulation in shoots. Overexpression of either OsHAC1;1 or OsHAC1;2 increases arsenite efflux, reduced As accumulation, and enhanced arsenate tolerance.

Literature References
PubMed ID Title Journal Year
27702843 OsHAC1;1 and OsHAC1;2 Function as Arsenate Reductases and Regulate Arsenic Accumulation Plant Physiol. 2016
External Reference Information
External Reference
UniProt:Q0E4S8 Os02g0102300
Gene Names
Os02g0102300, Os02g0102300, OSNPB_020102300
Participant Of
hasMember
Inferred To
GLYMA_02G047000 [cytosol] (Glycine max)
OE9A096142 [cytosol] (Olea europaea)
OE9A096142 [cytosol] (Olea europaea var. sylvestris)
Bo3g093800 [cytosol] (Brassica oleracea)
GLYMA_01G165300 [cytosol] (Glycine max)
GLYMA_16G126500 [cytosol] (Glycine max)
arahy.Tifrunner.gnm2.ann2.Ah05g045800 [cytosol] (Arachis hypogaea)
HanXRQr2_Chr14g0643061 [cytosol] (Helianthus annuus)
CICLE_v10026691mg [cytosol] (Citrus clementina)
g07193 [cytosol] (Arabidopsis halleri)
Csa15g076290 [cytosol] (Camelina sativa)
gene-LATHSAT_LOCUS15646 [cytosol] (Lathyrus sativus)
BGIOSGA007328 [cytosol] (Oryza sativa Indica Group)
EUGRSUZ_L00782 [cytosol] (Eucalyptus grandis)
MD15G0214000 [cytosol] (Malus domestica)
scaffold190.34 [cytosol] (Echinochloa crus-galli)
C5167_010398 [cytosol] (Papaver somniferum)
Sspon.04G0021130-1A [cytosol] (Saccharum spontaneum)
QL06p050815 [cytosol] (Quercus lobata)
TraesTSP7D01G172400 [cytosol] (Triticum spelta subsp. spelta)
AT5G66170 [cytosol] (Arabidopsis thaliana)
Vitvi04g02158 [cytosol] (Vitis vinifera)
Vradi11g06450 [cytosol] (Vigna radiata)
scaffold119.17 [cytosol] (Echinochloa crus-galli)
C5167_037847 [cytosol] (Papaver somniferum)
DCAR_016597 [cytosol] (Daucus carota)
TanjilG_28237 [cytosol] (Lupinus angustifolius)
NC9G0276270 [cytosol] (Nymphaea colorata)
NC9G0276290 [cytosol] (Nymphaea colorata)
OBART02G00230 [cytosol] (Oryza barthii)
AUR62029481 [cytosol] (Chenopodium quinoa)
gene-BT93_C1466 [cytosol] (Corymbia citriodora)
BVRB_6g130490 [cytosol] (Beta vulgaris)
scaffold361.36 [cytosol] (Echinochloa crus-galli)
Vfaba.Hedin2.R1.1g354240 [cytosol] (Vicia faba var. faba)
Vitvi04g02160 [cytosol] (Vitis vinifera)
CEY00_Acc24440 [cytosol] (Actinidia chinensis)
arahy.Tifrunner.gnm2.ann2.Ah11g003800 [cytosol] (Arachis hypogaea)
C.cajan_12515 [cytosol] (Cajanus cajan)
Vfaba.Hedin2.R1.Ung028240 [cytosol] (Vicia faba var. faba)
GSBRNA2T00042109001 [cytosol] (Brassica napus)
HORVU.MOREX.r3.7HG0659690 [cytosol] (Hordeum vulgare)
Potri.005G111200.v4.1 [cytosol] (Populus trichocarpa)
AVESA.00001b.r3.2Cg0000004 [cytosol] (Avena sativa)
TRIDC7AG018560 [cytosol] (Triticum dicoccoides)
Tp57577_TGAC_v2_gene19479 [cytosol] (Trifolium pratense)
Zm00001d025081 [cytosol] (Zea mays)
GSBRNA2T00081643001 [cytosol] (Brassica napus)
Vigun02g121700.v1.2 [cytosol] (Vigna unguiculata)
TRIDC6AG013750 [cytosol] (Triticum dicoccoides)
AMTR_s00018p00204090 [cytosol] (Amborella trichopoda)
Jr08_16760 [cytosol] (Juglans regia)
BRADI_3g00377v3 [cytosol] (Brachypodium distachyon)
EJB05_25564 [cytosol] (Eragrostis curvula)
Aradu.R57YU [cytosol] (Arachis duranensis)
Solyc02g083730.3 [cytosol] (Solanum lycopersicum)
LOC114381436 [cytosol] (Glycine soja)
Vradi07g01350 [cytosol] (Vigna radiata)
Psat2g153800 [cytosol] (Pisum sativum)
GSBRNA2T00022607001 [cytosol] (Brassica napus)
OB02G10250 [cytosol] (Oryza brachyantha)
HanXRQr2_Chr07g0294391 [cytosol] (Helianthus annuus)
GSCOC_T00037058001 [cytosol] (Coffea canephora)
Csa02g076640 [cytosol] (Camelina sativa)
Et_1B_012850 [cytosol] (Eragrostis tef)
gene48341 [cytosol] (Medicago truncatula)
GSBRNA2T00081641001 [cytosol] (Brassica napus)
GSBRNA2T00124958001 [cytosol] (Brassica napus)
LR48_Vigan01g176000 [cytosol] (Vigna angularis)
TCM_000187 [cytosol] (Theobroma cacao)
fgenesh2_kg.8__2814__AT5G66170.1 [cytosol] (Arabidopsis lyrata)
gene29355 [cytosol] (Medicago truncatula)
BjuA02g00060S [cytosol] (Brassica juncea)
Vitvi04g02159 [cytosol] (Vitis vinifera)
AUR62003355 [cytosol] (Chenopodium quinoa)
arahy.Tifrunner.gnm2.ann2.Ah15g045800 [cytosol] (Arachis hypogaea)
NC9G0276280 [cytosol] (Nymphaea colorata)
Sspon.04G0021130-2B [cytosol] (Saccharum spontaneum)
Zm00001eb420080 [cytosol] (Zea mays ver5)
PHAVU_002G107700g [cytosol] (Phaseolus vulgaris)
Psat4g100800 [cytosol] (Pisum sativum)
OGLUM02G00220 [cytosol] (Oryza glumaepatula)
SIN_1025320 [cytosol] (Sesamum indicum)
Jr08_16770 [cytosol] (Juglans regia)
OMERI02G00210 [cytosol] (Oryza meridionalis)
B456_007G049000 [cytosol] (Gossypium raimondii)
ONIVA02G00240 [cytosol] (Oryza nivara)
evm.TU.01.532 [cytosol] (Cannabis sativa)
MD02G0111000 [cytosol] (Malus domestica)
Tritim_EIv0.3_1401960 [cytosol] (Triticum timopheevii subsp. timopheevii)
PRUPE_7G170100 [cytosol] (Prunus persica)
itb05g24540 [cytosol] (Ipomoea triloba)
Bo2g167600 [cytosol] (Brassica oleracea)
gene-CFP56_16054 [cytosol] (Quercus suber)
OPUNC11G05550 [cytosol] (Oryza punctata)
GSBRNA2T00016402001 [cytosol] (Brassica napus)
C.cajan_41350 [cytosol] (Cajanus cajan)
TuG1812G0700001583.01 [cytosol] (Triticum urartu)
SIN_1009437 [cytosol] (Sesamum indicum)
Tp57577_TGAC_v2_gene31341 [cytosol] (Trifolium pratense)
gene-LATHSAT_LOCUS9058 [cytosol] (Lathyrus sativus)
LOC114374716 [cytosol] (Glycine soja)
Bo7g065090 [cytosol] (Brassica oleracea)
A06p041160.1_BraROA [cytosol] (Brassica rapa)
ORGLA02G0001600 [cytosol] (Oryza glaberrima)
Homologues of HAC1;1 [cytosol] (Arabidopsis lyrata)
Homologues of HAC1;1 [cytosol] (Arabidopsis thaliana)
Homologues of HAC1;1 [cytosol] (Arachis hypogaea)
Homologues of HAC1;1 [cytosol] (Avena sativa)
Homologues of HAC1;1 [cytosol] (Brassica napus)
Homologues of HAC1;1 [cytosol] (Brassica oleracea)
Homologues of HAC1;1 [cytosol] (Brassica rapa)
Homologues of HAC1;1 [cytosol] (Cajanus cajan)
Homologues of HAC1;1 [cytosol] (Camelina sativa)
Homologues of HAC1;1 [cytosol] (Chenopodium quinoa)
Homologues of HAC1;1 [cytosol] (Daucus carota)
Homologues of HAC1;1 [cytosol] (Echinochloa crus-galli)
Homologues of HAC1;1 [cytosol] (Ficus carica)
Homologues of HAC1;1 [cytosol] (Glycine max)
Homologues of HAC1;1 [cytosol] (Glycine soja)
Homologues of HAC1;1 [cytosol] (Helianthus annuus)
Homologues of HAC1;1 [cytosol] (Juglans regia)
Homologues of HAC1;1 [cytosol] (Lactuca sativa)
Homologues of HAC1;1 [cytosol] (Lathyrus sativus)
Homologues of HAC1;1 [cytosol] (Malus domestica)
Homologues of HAC1;1 [cytosol] (Medicago truncatula)
Homologues of HAC1;1 [cytosol] (Nymphaea colorata)
Homologues of HAC1;1 [cytosol] (Papaver somniferum)
Homologues of HAC1;1 [cytosol] (Phaseolus vulgaris)
Homologues of HAC1;1 [cytosol] (Pisum sativum)
Homologues of HAC1;1 [cytosol] (Quercus suber)
Homologues of HAC1;1 [cytosol] (Saccharum spontaneum)
Homologues of HAC1;1 [cytosol] (Sesamum indicum)
Homologues of HAC1;1 [cytosol] (Trifolium pratense)
Homologues of HAC1;1 [cytosol] (Triticum dicoccoides)
Homologues of HAC1;1 [cytosol] (Triticum spelta subsp. spelta)
Homologues of HAC1;1 [cytosol] (Vicia faba var. faba)
Homologues of HAC1;1 [cytosol] (Vigna angularis)
Homologues of HAC1;1 [cytosol] (Vigna radiata)
Homologues of HAC1;1 [cytosol] (Vigna unguiculata)
Homologues of HAC1;1 [cytosol] (Vitis vinifera)
Csa01g039790 [cytosol] (Camelina sativa)
Ma05_g21270 [cytosol] (Musa acuminata)
LOC114419752 [cytosol] (Glycine soja)
SEVIR_1G001900v2 [cytosol] (Setaria viridis)
gene-LSAT_2X76100 [cytosol] (Lactuca sativa)
GLYMA_11G077900 [cytosol] (Glycine max)
AT2G17850 [cytosol] (Arabidopsis thaliana)
RchiOBHm_Chr2g0099231 [cytosol] (Rosa chinensis)
LR48_Vigan499s002000 [cytosol] (Vigna angularis)
Csa11g104800 [cytosol] (Camelina sativa)
arahy.Tifrunner.gnm2.ann2.Ah01g097200 [cytosol] (Arachis hypogaea)
A02p060470.1_BraROA [cytosol] (Brassica rapa)
LOC114389032 [cytosol] (Glycine soja)
DCAR_016598 [cytosol] (Daucus carota)
gene-LSAT_2X76060 [cytosol] (Lactuca sativa)
gene-LATHSAT_LOCUS9057 [cytosol] (Lathyrus sativus)
A07p023320.1_BraROA [cytosol] (Brassica rapa)
FRAEX38873_v2_000091570 [cytosol] (Fraxinus excelsior (European ash))
SORBI_3004G002600 [cytosol] (Sorghum bicolor)
Tp57577_TGAC_v2_gene31335 [cytosol] (Trifolium pratense)
T459_06213 [cytosol] (Capsicum annuum)
PGSC0003DMG400003573 [cytosol] (Solanum tuberosum)
TraesTSP7B01G057100 [cytosol] (Triticum spelta subsp. spelta)
A4A49_02111 [cytosol] (Nicotiana attenuata)
PHAVU_003G264200g [cytosol] (Phaseolus vulgaris)
GSBRNA2T00046213001 [cytosol] (Brassica napus)
FCD_00030194 [cytosol] (Ficus carica)
Al_scaffold_0003_3745 [cytosol] (Arabidopsis lyrata)
EVM0006181 [cytosol] (Pistacia vera)
SETIT_031418mg [cytosol] (Setaria italica)
ORUFI02G00240 [cytosol] (Oryza rufipogon)
Vfaba.Hedin2.R1.1g354280 [cytosol] (Vicia faba var. faba)
Sspon.05G0013570-1P [cytosol] (Saccharum spontaneum)
Tp57577_TGAC_v2_gene31338 [cytosol] (Trifolium pratense)
FCD_00008573 [cytosol] (Ficus carica)
Manes.01G147900.v8.1 [cytosol] (Manihot esculenta)
Jr_Scaffold_258_00010 [cytosol] (Juglans regia)
Csa18g042370 [cytosol] (Camelina sativa)
Psat2g153680 [cytosol] (Pisum sativum)
Ccrd_012854 [cytosol] (Cynara cardunculus var. scolymus)
AVESA.00001b.r3.4Cg0000461 [cytosol] (Avena sativa)
Jr_Scaffold_258_00020 [cytosol] (Juglans regia)
Vigun03g257200.v1.2 [cytosol] (Vigna unguiculata)
gene-CFP56_62602 [cytosol] (Quercus suber)