Isovaleryl-CoA dehydrogenase

Stable Identifier
R-OSA-9611863
Type
Protein [EntityWithAccessionedSequence]
Species
Oryza sativa
Locations in the PathwayBrowser
Summation

Enzyme conmmision transferred EC number1.3.99.10 of Isovaleryl-CoA dehydrogenase enzyme to 1.3.8.4.

Substrate specificity tests of Arabidopsis isovaleryl-CoA dehydrogenase (IVD) expressed in Escherichia coli showed a strong preference toward isovaleryl-CoA but also show considerable activity with isobutyryl-CoA. This strongly indicates that this enzyme has parallel activity towards isovaleryl-CoA and isobutyryl-CoA, thus involved in both pathways- leucine and valine catabolism. Such dual activity has not been observed with the animal IVD and may suggest a novel connection of the Leu and valine catabolism in plants.

External Reference Information
External Reference
Gene Names
Os05g0125500, OsJ_16966, OSJNBb0079L11.8, P0683F12.2
Chain
transit peptide:1-22, chain:23-409
Inferred To