ADP-glucose pyrophosphorylase (AGPase)

Stable Identifier
R-OSA-1120965
Type
Reaction
Species
Oryza sativa
Compartment
cytosol
Synonyms
Glucose-1-phosphate adenylyltransferase, ADP-glucose diphosphorylase, ADP-glucose synthase, biochemicalReaction56320
Locations in the PathwayBrowser
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Summation

In higher plants, ADP-glucose pyrophosphorylase (AGPase) catalyzes the first committed step of starch biosynthesis by converting Alpha-D-glucose 1-phosphate (G1P) to ADP-glucose. AGPase reaction occurs in the plastid and in the cytosol of the cereal endosperm; however, ADP-glucose from the cytosol is transported to amyloplast by the ADP-glucose transporter encoded by the rice Brittle1 (OsBT1) gene. AGPase is also known as Glucose-1-phosphate adenylyltransferase. AGPase is a heterotetramer composed of two small (AGPS ) and two large (AGPL) subunits (Lee et al., 2007, and Figuera et al, 2022). The rice genome contains two genes encoding small subunits, OsAGPS1 and OsAGPS2, and four genes encoding large subunits, OsAGPL1, OsAGPL2, OsAGPL3, and OsAGPL4. OsAGPS2a (the product of the leaf-preferential transcript of OsAGPS2), and OsAGPS1, OsAGPL1, OsAGPL3, and OsAGPL4 are plastid-targeted isoforms. However, OsAGPS2b (a product of a seed-specific transcript of OsAGPS2) and OsAGPL2 are found in the cytosol (Lee et al., 2007). The rice osagps2 and osagpl2 mutants affect OsAGPL2 and OsAGPS2b, causing a shrunken endosperm due to a decrease in starch synthesis (Lee et al., 2007). On the other hand, a mutation in the plastid AGPase subunits causes disruption in root gravitropism leading to the gravitropic phenotype (Zhang et al., 2019).

Literature References
Participants
Input
Output
Participant Of
hasEvent
Event Information
Go Biological Process
starch biosynthetic process (0019252)
Catalyst Activity
Catalyst Activity
Title
glucose-1-phosphate adenylyltransferase activity of AGPase-cytosolic [cytosol]
Physical Entity
AGPase-cytosolic [cytosol]
Activity
glucose-1-phosphate adenylyltransferase activity (0008878)
Orthologous Events
ADP-glucose pyrophosphorylase (AGPase) (Actinidia chinensis)
ADP-glucose pyrophosphorylase (AGPase) (Aegilops tauschii)
ADP-glucose pyrophosphorylase (AGPase) (Aegilops umbellulata)
ADP-glucose pyrophosphorylase (AGPase) (Amborella trichopoda)
ADP-glucose pyrophosphorylase (AGPase) (Ananas comosus)
ADP-glucose pyrophosphorylase (AGPase) (Arabidopsis halleri)
ADP-glucose pyrophosphorylase (AGPase) (Arabidopsis lyrata)
ADP-glucose pyrophosphorylase (AGPase) (Arabidopsis thaliana)
ADP-glucose pyrophosphorylase (AGPase) (Arachis duranensis)
ADP-glucose pyrophosphorylase (AGPase) (Arachis hypogaea)
ADP-glucose pyrophosphorylase (AGPase) (Arachis ipaensis)
ADP-glucose pyrophosphorylase (AGPase) (Asparagus officinalis)
ADP-glucose pyrophosphorylase (AGPase) (Avena sativa)
ADP-glucose pyrophosphorylase (AGPase) (Beta vulgaris)
ADP-glucose pyrophosphorylase (AGPase) (Brachypodium distachyon)
ADP-glucose pyrophosphorylase (AGPase) (Brassica juncea)
ADP-glucose pyrophosphorylase (AGPase) (Brassica napus)
ADP-glucose pyrophosphorylase (AGPase) (Brassica oleracea)
ADP-glucose pyrophosphorylase (AGPase) (Brassica rapa)
ADP-glucose pyrophosphorylase (AGPase) (Cajanus cajan)
ADP-glucose pyrophosphorylase (AGPase) (Camelina sativa)
ADP-glucose pyrophosphorylase (AGPase) (Cannabis sativa)
ADP-glucose pyrophosphorylase (AGPase) (Cannabis sativa subsp. indica)
ADP-glucose pyrophosphorylase (AGPase) (Capsella rubella)
ADP-glucose pyrophosphorylase (AGPase) (Capsicum annuum)
ADP-glucose pyrophosphorylase (AGPase) (Chara braunii)
ADP-glucose pyrophosphorylase (AGPase) (Chenopodium quinoa)
ADP-glucose pyrophosphorylase (AGPase) (Chlamydomonas reinhardtii)
ADP-glucose pyrophosphorylase (AGPase) (Cicer arietinum)
ADP-glucose pyrophosphorylase (AGPase) (Citrullus lanatus)
ADP-glucose pyrophosphorylase (AGPase) (Citrus clementina)
ADP-glucose pyrophosphorylase (AGPase) (Citrus sinensis)
ADP-glucose pyrophosphorylase (AGPase) (Coffea canephora)
ADP-glucose pyrophosphorylase (AGPase) (Corchorus capsularis)
ADP-glucose pyrophosphorylase (AGPase) (Corchorus olitorius)
ADP-glucose pyrophosphorylase (AGPase) (Corymbia citriodora)
ADP-glucose pyrophosphorylase (AGPase) (Cucumis melo)
ADP-glucose pyrophosphorylase (AGPase) (Cucumis sativus)
ADP-glucose pyrophosphorylase (AGPase) (Cynara cardunculus var. scolymus)
ADP-glucose pyrophosphorylase (AGPase) (Daucus carota)
ADP-glucose pyrophosphorylase (AGPase) (Digitaria exilis)
ADP-glucose pyrophosphorylase (AGPase) (Dioscorea rotundata)
ADP-glucose pyrophosphorylase (AGPase) (Echinochloa crus-galli)
ADP-glucose pyrophosphorylase (AGPase) (Eragrostis curvula)
ADP-glucose pyrophosphorylase (AGPase) (Eragrostis tef)
ADP-glucose pyrophosphorylase (AGPase) (Erythranthe guttata)
ADP-glucose pyrophosphorylase (AGPase) (Eucalyptus grandis)
ADP-glucose pyrophosphorylase (AGPase) (Ficus carica)
ADP-glucose pyrophosphorylase (AGPase) (Fragaria vesca)
ADP-glucose pyrophosphorylase (AGPase) (Fraxinus excelsior (European ash))
ADP-glucose pyrophosphorylase (AGPase) (Glycine max)
ADP-glucose pyrophosphorylase (AGPase) (Glycine soja)
ADP-glucose pyrophosphorylase (AGPase) (Gossypium raimondii)
ADP-glucose pyrophosphorylase (AGPase) (Helianthus annuus)
ADP-glucose pyrophosphorylase (AGPase) (Hordeum vulgare)
ADP-glucose pyrophosphorylase (AGPase) (Humulus lupulus)
ADP-glucose pyrophosphorylase (AGPase) (Humulus lupulus var. lupulus)
ADP-glucose pyrophosphorylase (AGPase) (Ipomoea triloba)
ADP-glucose pyrophosphorylase (AGPase) (Jatropha curcas)
ADP-glucose pyrophosphorylase (AGPase) (Juglans regia)
ADP-glucose pyrophosphorylase (AGPase) (Lactuca sativa)
ADP-glucose pyrophosphorylase (AGPase) (Lathyrus sativus)
ADP-glucose pyrophosphorylase (AGPase) (Leersia perrieri)
ADP-glucose pyrophosphorylase (AGPase) (Lolium perenne)
ADP-glucose pyrophosphorylase (AGPase) (Lupinus angustifolius)
ADP-glucose pyrophosphorylase (AGPase) (Malus domestica)
ADP-glucose pyrophosphorylase (AGPase) (Manihot esculenta)
ADP-glucose pyrophosphorylase (AGPase) (Marchantia polymorpha)
ADP-glucose pyrophosphorylase (AGPase) (Medicago truncatula)
ADP-glucose pyrophosphorylase (AGPase) (Musa acuminata)
ADP-glucose pyrophosphorylase (AGPase) (Nelumbo nucifera)
ADP-glucose pyrophosphorylase (AGPase) (Nicotiana attenuata)
ADP-glucose pyrophosphorylase (AGPase) (Nymphaea colorata)
ADP-glucose pyrophosphorylase (AGPase) (Olea europaea)
ADP-glucose pyrophosphorylase (AGPase) (Olea europaea var. sylvestris)
ADP-glucose pyrophosphorylase (AGPase) (Oryza australiensis)
ADP-glucose pyrophosphorylase (AGPase) (Oryza barthii)
ADP-glucose pyrophosphorylase (AGPase) (Oryza brachyantha)
ADP-glucose pyrophosphorylase (AGPase) (Oryza glaberrima)
ADP-glucose pyrophosphorylase (AGPase) (Oryza glumaepatula)
ADP-glucose pyrophosphorylase (AGPase) (Oryza longistaminata)
ADP-glucose pyrophosphorylase (AGPase) (Oryza meridionalis)
ADP-glucose pyrophosphorylase (AGPase) (Oryza meyeriana var. granulata)
ADP-glucose pyrophosphorylase (AGPase) (Oryza minuta)
ADP-glucose pyrophosphorylase (AGPase) (Oryza nivara)
ADP-glucose pyrophosphorylase (AGPase) (Oryza officinalis)
ADP-glucose pyrophosphorylase (AGPase) (Oryza punctata)
ADP-glucose pyrophosphorylase (AGPase) (Oryza rufipogon)
ADP-glucose pyrophosphorylase (AGPase) (Oryza sativa Indica Group)
ADP-glucose pyrophosphorylase (AGPase) (Oryza sativa aus subgroup)
ADP-glucose pyrophosphorylase (AGPase) (Ostreococcus lucimarinus)
ADP-glucose pyrophosphorylase (AGPase) (Panicum hallii ("FIL2"))
ADP-glucose pyrophosphorylase (AGPase) (Panicum hallii var. hallii ("HAL2"))
ADP-glucose pyrophosphorylase (AGPase) (Papaver somniferum)
ADP-glucose pyrophosphorylase (AGPase) (Phaseolus vulgaris)
ADP-glucose pyrophosphorylase (AGPase) (Phoenix dactylifera)
ADP-glucose pyrophosphorylase (AGPase) (Phyllostachys edulis)
ADP-glucose pyrophosphorylase (AGPase) (Physcomitrella patens)
ADP-glucose pyrophosphorylase (AGPase) (Picea abies)
ADP-glucose pyrophosphorylase (AGPase) (Pinus taeda)
ADP-glucose pyrophosphorylase (AGPase) (Pistacia vera)
ADP-glucose pyrophosphorylase (AGPase) (Pisum sativum)
ADP-glucose pyrophosphorylase (AGPase) (Populus trichocarpa)
ADP-glucose pyrophosphorylase (AGPase) (Prunus avium)
ADP-glucose pyrophosphorylase (AGPase) (Prunus persica)
ADP-glucose pyrophosphorylase (AGPase) (Quercus lobata)
ADP-glucose pyrophosphorylase (AGPase) (Quercus suber)
ADP-glucose pyrophosphorylase (AGPase) (Rosa chinensis)
ADP-glucose pyrophosphorylase (AGPase) (Saccharum spontaneum)
ADP-glucose pyrophosphorylase (AGPase) (Salvia hispanica)
ADP-glucose pyrophosphorylase (AGPase) (Secale cereale)
ADP-glucose pyrophosphorylase (AGPase) (Selaginella moellendorffii)
ADP-glucose pyrophosphorylase (AGPase) (Sesamum indicum)
ADP-glucose pyrophosphorylase (AGPase) (Setaria italica)
ADP-glucose pyrophosphorylase (AGPase) (Setaria viridis)
ADP-glucose pyrophosphorylase (AGPase) (Solanum lycopersicum)
ADP-glucose pyrophosphorylase (AGPase) (Solanum tuberosum)
ADP-glucose pyrophosphorylase (AGPase) (Sorghum bicolor)
ADP-glucose pyrophosphorylase (AGPase) (Synechocystis sp. PCC 6803)
ADP-glucose pyrophosphorylase (AGPase) (Theobroma cacao)
ADP-glucose pyrophosphorylase (AGPase) (Trifolium pratense)
ADP-glucose pyrophosphorylase (AGPase) (Triticum aestivum)
ADP-glucose pyrophosphorylase (AGPase) (Triticum dicoccoides)
ADP-glucose pyrophosphorylase (AGPase) (Triticum spelta subsp. spelta)
ADP-glucose pyrophosphorylase (AGPase) (Triticum timopheevii subsp. timopheevii)
ADP-glucose pyrophosphorylase (AGPase) (Triticum turgidum)
ADP-glucose pyrophosphorylase (AGPase) (Triticum urartu)
ADP-glucose pyrophosphorylase (AGPase) (Vicia faba var. faba)
ADP-glucose pyrophosphorylase (AGPase) (Vigna angularis)
ADP-glucose pyrophosphorylase (AGPase) (Vigna radiata)
ADP-glucose pyrophosphorylase (AGPase) (Vigna unguiculata)
ADP-glucose pyrophosphorylase (AGPase) (Vitis vinifera)
ADP-glucose pyrophosphorylase (AGPase) (Zea mays)
ADP-glucose pyrophosphorylase (AGPase) (Zea mays ver5)
ADP-glucose pyrophosphorylase (AGPase) (Zoysia japonica)
Cross References
RiceCyc
EC