Vitamin E biosynthesis

Stable Identifier
R-OSA-1119287
Type
Pathway
Species
Oryza sativa
Compartment
chloroplast, cytosol
Synonyms
Tocopherol biosynthesis, pathway101353
Locations in the PathwayBrowser
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Summation

Vitamin E biosynthesis is initiated in the plant?s cytoplasm, but, except for the first step, biosynthesis takes place in the plastids. The necessary enzymes are localized at the inner membrane of chloroplast (Fritsche et al., 2017). Tocopherol (Vit. E) synthesis is initiated by homogentisate phytyltransferase (HPT) that condense homogentisate (HGA) and phytyl pyrophosphate (PPP). The condensation reaction between HGA and polyprenyl pyrophosphate produces 2-methyl-6-phytyl-1,4-benzoquinol (MPBQ), or can be direct precursors of ?- and ?-tocopherols, or can alternatively be methylated by a methyltransferase (MT/VTE3). The products of the later reaction are prenylated dimethyl-benzoquinols, namely 2,3-dimethyl-6-phytyl-1,4-benzoquinol (DMPBQ) which further cyclized by the tocopherol cyclase (TC/VTE1) to ?-tocopherol. The final step of Vit. E biosynthesis consists of the methylation of ?- and ?-tocopherols into ?- and ?-tocopherols (Mène-Saffrané 2017).

Literature References
Participants
Events
Participant Of
hasEvent
Event Information
Go Biological Process
vitamin E biosynthetic process (0010189)
Orthologous Events
Vitamin E biosynthesis (Actinidia chinensis)
Vitamin E biosynthesis (Aegilops tauschii)
Vitamin E biosynthesis (Aegilops umbellulata)
Vitamin E biosynthesis (Amborella trichopoda)
Vitamin E biosynthesis (Ananas comosus)
Vitamin E biosynthesis (Arabidopsis halleri)
Vitamin E biosynthesis (Arabidopsis lyrata)
Vitamin E biosynthesis (Arabidopsis thaliana)
Vitamin E biosynthesis (Arachis duranensis)
Vitamin E biosynthesis (Arachis hypogaea)
Vitamin E biosynthesis (Arachis ipaensis)
Vitamin E biosynthesis (Asparagus officinalis)
Vitamin E biosynthesis (Avena sativa)
Vitamin E biosynthesis (Beta vulgaris)
Vitamin E biosynthesis (Brachypodium distachyon)
Vitamin E biosynthesis (Brassica juncea)
Vitamin E biosynthesis (Brassica napus)
Vitamin E biosynthesis (Brassica oleracea)
Vitamin E biosynthesis (Brassica rapa)
Vitamin E biosynthesis (Cajanus cajan)
Vitamin E biosynthesis (Camelina sativa)
Vitamin E biosynthesis (Cannabis sativa)
Vitamin E biosynthesis (Cannabis sativa subsp. indica)
Vitamin E biosynthesis (Capsella rubella)
Vitamin E biosynthesis (Capsicum annuum)
Vitamin E biosynthesis (Chara braunii)
Vitamin E biosynthesis (Chenopodium quinoa)
Vitamin E biosynthesis (Chlamydomonas reinhardtii)
Vitamin E biosynthesis (Chondrus crispus)
Vitamin E biosynthesis (Cicer arietinum)
Vitamin E biosynthesis (Citrullus lanatus)
Vitamin E biosynthesis (Citrus clementina)
Vitamin E biosynthesis (Citrus sinensis)
Vitamin E biosynthesis (Coffea canephora)
Vitamin E biosynthesis (Corchorus capsularis)
Vitamin E biosynthesis (Corchorus olitorius)
Vitamin E biosynthesis (Corymbia citriodora)
Vitamin E biosynthesis (Cucumis melo)
Vitamin E biosynthesis (Cucumis sativus)
Vitamin E biosynthesis (Cyanidioschyzon merolae)
Vitamin E biosynthesis (Cynara cardunculus var. scolymus)
Vitamin E biosynthesis (Daucus carota)
Vitamin E biosynthesis (Digitaria exilis)
Vitamin E biosynthesis (Dioscorea rotundata)
Vitamin E biosynthesis (Echinochloa crus-galli)
Vitamin E biosynthesis (Eragrostis curvula)
Vitamin E biosynthesis (Eragrostis tef)
Vitamin E biosynthesis (Erythranthe guttata)
Vitamin E biosynthesis (Eucalyptus grandis)
Vitamin E biosynthesis (Ficus carica)
Vitamin E biosynthesis (Fragaria vesca)
Vitamin E biosynthesis (Fraxinus excelsior (European ash))
Vitamin E biosynthesis (Galdieria sulphuraria)
Vitamin E biosynthesis (Glycine max)
Vitamin E biosynthesis (Glycine soja)
Vitamin E biosynthesis (Gossypium raimondii)
Vitamin E biosynthesis (Helianthus annuus)
Vitamin E biosynthesis (Hordeum vulgare)
Vitamin E biosynthesis (Humulus lupulus)
Vitamin E biosynthesis (Humulus lupulus var. lupulus)
Vitamin E biosynthesis (Ipomoea triloba)
Vitamin E biosynthesis (Jatropha curcas)
Vitamin E biosynthesis (Juglans regia)
Vitamin E biosynthesis (Lactuca sativa)
Vitamin E biosynthesis (Lathyrus sativus)
Vitamin E biosynthesis (Leersia perrieri)
Vitamin E biosynthesis (Lolium perenne)
Vitamin E biosynthesis (Lupinus angustifolius)
Vitamin E biosynthesis (Malus domestica)
Vitamin E biosynthesis (Manihot esculenta)
Vitamin E biosynthesis (Marchantia polymorpha)
Vitamin E biosynthesis (Medicago truncatula)
Vitamin E biosynthesis (Musa acuminata)
Vitamin E biosynthesis (Nelumbo nucifera)
Vitamin E biosynthesis (Nicotiana attenuata)
Vitamin E biosynthesis (Nymphaea colorata)
Vitamin E biosynthesis (Olea europaea)
Vitamin E biosynthesis (Olea europaea var. sylvestris)
Vitamin E biosynthesis (Oryza australiensis)
Vitamin E biosynthesis (Oryza barthii)
Vitamin E biosynthesis (Oryza brachyantha)
Vitamin E biosynthesis (Oryza glaberrima)
Vitamin E biosynthesis (Oryza glumaepatula)
Vitamin E biosynthesis (Oryza longistaminata)
Vitamin E biosynthesis (Oryza meridionalis)
Vitamin E biosynthesis (Oryza meyeriana var. granulata)
Vitamin E biosynthesis (Oryza minuta)
Vitamin E biosynthesis (Oryza nivara)
Vitamin E biosynthesis (Oryza officinalis)
Vitamin E biosynthesis (Oryza punctata)
Vitamin E biosynthesis (Oryza rufipogon)
Vitamin E biosynthesis (Oryza sativa Indica Group)
Vitamin E biosynthesis (Oryza sativa aus subgroup)
Vitamin E biosynthesis (Ostreococcus lucimarinus)
Vitamin E biosynthesis (Panicum hallii ("FIL2"))
Vitamin E biosynthesis (Panicum hallii var. hallii ("HAL2"))
Vitamin E biosynthesis (Papaver somniferum)
Vitamin E biosynthesis (Phaseolus vulgaris)
Vitamin E biosynthesis (Phoenix dactylifera)
Vitamin E biosynthesis (Phyllostachys edulis)
Vitamin E biosynthesis (Physcomitrella patens)
Vitamin E biosynthesis (Picea abies)
Vitamin E biosynthesis (Pinus taeda)
Vitamin E biosynthesis (Pistacia vera)
Vitamin E biosynthesis (Pisum sativum)
Vitamin E biosynthesis (Populus trichocarpa)
Vitamin E biosynthesis (Prunus avium)
Vitamin E biosynthesis (Prunus persica)
Vitamin E biosynthesis (Quercus lobata)
Vitamin E biosynthesis (Quercus suber)
Vitamin E biosynthesis (Rosa chinensis)
Vitamin E biosynthesis (Saccharum spontaneum)
Vitamin E biosynthesis (Salvia hispanica)
Vitamin E biosynthesis (Secale cereale)
Vitamin E biosynthesis (Selaginella moellendorffii)
Vitamin E biosynthesis (Sesamum indicum)
Vitamin E biosynthesis (Setaria italica)
Vitamin E biosynthesis (Setaria viridis)
Vitamin E biosynthesis (Solanum lycopersicum)
Vitamin E biosynthesis (Solanum tuberosum)
Vitamin E biosynthesis (Sorghum bicolor)
Vitamin E biosynthesis (Synechocystis sp. PCC 6803)
Vitamin E biosynthesis (Theobroma cacao)
Vitamin E biosynthesis (Trifolium pratense)
Vitamin E biosynthesis (Triticum aestivum)
Vitamin E biosynthesis (Triticum dicoccoides)
Vitamin E biosynthesis (Triticum spelta subsp. spelta)
Vitamin E biosynthesis (Triticum timopheevii subsp. timopheevii)
Vitamin E biosynthesis (Triticum turgidum)
Vitamin E biosynthesis (Triticum urartu)
Vitamin E biosynthesis (Vicia faba var. faba)
Vitamin E biosynthesis (Vigna angularis)
Vitamin E biosynthesis (Vigna radiata)
Vitamin E biosynthesis (Vigna unguiculata)
Vitamin E biosynthesis (Vitis vinifera)
Vitamin E biosynthesis (Zea mays)
Vitamin E biosynthesis (Zea mays ver5)
Vitamin E biosynthesis (Zoysia japonica)
Cross References
RiceCyc