Plant Reactome Pathway Database - Plant Reactome Pathway Database

origin of replication

Stable Identifier

R-ALL-68419

Type

OtherEntity

Synonyms

origin, autonomously replicating sequence, ARS

Locations in the PathwayBrowser

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Cellular processes (Oryza sativa)

- DNA replication: activation of the pre-replicative complex (Oryza sativa)
  - Cdc45 associates with the pre-replicative complex at the origin (Oryza sativa)
    - CDK:DDK:Mcm10:pre-replicative complex (name copied from entity in Homo sapiens) [nucleoplasm] (Oryza sativa)
      - Mcm10:active pre-replicative complex (name copied from entity in Homo sapiens) [nucleoplasm] (Oryza sativa)
        
        active pre-replicative complex (name copied from entity in Homo sapiens) [nucleoplasm] (Oryza sativa)
        
        CDC6:ORC:origin complex (name copied from entity in Homo sapiens) [nucleoplasm] (Oryza sativa)
        
        ORC:origin (name copied from entity in Homo sapiens) [nucleoplasm] (Oryza sativa)
        
        origin of replication [nucleoplasm]
    - Cdc45:CDK:DDK:Mcm10:pre-replicative complex (name copied from entity in Homo sapiens) [nucleoplasm] (Oryza sativa)
      - CDK:DDK:Mcm10:pre-replicative complex (name copied from entity in Homo sapiens) [nucleoplasm] (Oryza sativa)
        
        Mcm10:active pre-replicative complex (name copied from entity in Homo sapiens) [nucleoplasm] (Oryza sativa)
        
        active pre-replicative complex (name copied from entity in Homo sapiens) [nucleoplasm] (Oryza sativa)
        
        CDC6:ORC:origin complex (name copied from entity in Homo sapiens) [nucleoplasm] (Oryza sativa)
        
        ORC:origin (name copied from entity in Homo sapiens) [nucleoplasm] (Oryza sativa)
        
        origin of replication [nucleoplasm]
  - DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin (Oryza sativa)
    - Cdc45:CDK:DDK:Mcm10:pre-replicative complex (name copied from entity in Homo sapiens) [nucleoplasm] (Oryza sativa)
      - CDK:DDK:Mcm10:pre-replicative complex (name copied from entity in Homo sapiens) [nucleoplasm] (Oryza sativa)
        
        Mcm10:active pre-replicative complex (name copied from entity in Homo sapiens) [nucleoplasm] (Oryza sativa)
        
        active pre-replicative complex (name copied from entity in Homo sapiens) [nucleoplasm] (Oryza sativa)
        
        CDC6:ORC:origin complex (name copied from entity in Homo sapiens) [nucleoplasm] (Oryza sativa)
        
        ORC:origin (name copied from entity in Homo sapiens) [nucleoplasm] (Oryza sativa)
        
        origin of replication [nucleoplasm]
    - RPA:Cdc45:CDK:DDK:Mcm10:pre-replicative complex (name copied from entity in Homo sapiens) [nucleoplasm] (Oryza sativa)
      - Cdc45:CDK:DDK:Mcm10:pre-replicative complex (name copied from entity in Homo sapiens) [nucleoplasm] (Oryza sativa)
        
        CDK:DDK:Mcm10:pre-replicative complex (name copied from entity in Homo sapiens) [nucleoplasm] (Oryza sativa)
        
        Mcm10:active pre-replicative complex (name copied from entity in Homo sapiens) [nucleoplasm] (Oryza sativa)
        
        active pre-replicative complex (name copied from entity in Homo sapiens) [nucleoplasm] (Oryza sativa)
        
        CDC6:ORC:origin complex (name copied from entity in Homo sapiens) [nucleoplasm] (Oryza sativa)
        
        ORC:origin (name copied from entity in Homo sapiens) [nucleoplasm] (Oryza sativa)
        
        origin of replication [nucleoplasm]
  - DNA polymerase alpha:primase binds at the origin (Oryza sativa)
    - DNA polymerase alpha:primase:DNA polymerase alpha:origin complex (name copied from entity in Homo sapiens) [nucleoplasm] (Oryza sativa)
      - DNA polymerase epsilon:origin complex (name copied from entity in Homo sapiens) [nucleoplasm] (Oryza sativa)
        
        origin of replication [nucleoplasm]
    - DNA polymerase epsilon:origin complex (name copied from entity in Homo sapiens) [nucleoplasm] (Oryza sativa)
      - origin of replication [nucleoplasm]
  - DNA polymerase epsilon binds at the origin (Oryza sativa)
    - origin of replication [nucleoplasm]
    - DNA polymerase epsilon:origin complex (name copied from entity in Homo sapiens) [nucleoplasm] (Oryza sativa)
      - origin of replication [nucleoplasm]
  - Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7 (Oryza sativa)
    - Mcm10:pre-replicative complex (name copied from entity in Homo sapiens) [nucleoplasm] (Oryza sativa)
      - pre-replicative complex (name copied from entity in Homo sapiens) [nucleoplasm] (Oryza sativa)
        
        CDT1:CDC6:ORC:origin complex (name copied from entity in Homo sapiens) [nucleoplasm] (Oryza sativa)
        
        CDC6:ORC:origin complex (name copied from entity in Homo sapiens) [nucleoplasm] (Oryza sativa)
        
        ORC:origin (name copied from entity in Homo sapiens) [nucleoplasm] (Oryza sativa)
        
        origin of replication [nucleoplasm]
    - pre-replicative complex (name copied from entity in Homo sapiens) [nucleoplasm] (Oryza sativa)
      - CDT1:CDC6:ORC:origin complex (name copied from entity in Homo sapiens) [nucleoplasm] (Oryza sativa)
        
        CDC6:ORC:origin complex (name copied from entity in Homo sapiens) [nucleoplasm] (Oryza sativa)
        
        ORC:origin (name copied from entity in Homo sapiens) [nucleoplasm] (Oryza sativa)
        
        origin of replication [nucleoplasm]

Participant Of

input

DNA polymerase epsilon binds at the origin

hasComponent

Cross References

ChEBI

61120